Goossens Ellen, Tournaye Herman
Research group biology of testis, department of embryology and genetics, Vrije universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium.
Research group biology of testis, department of embryology and genetics, Vrije universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium.
Ann Endocrinol (Paris). 2014 May;75(2):115-7. doi: 10.1016/j.ando.2014.03.011. Epub 2014 Apr 29.
Male fertility preservation receives growing attention in the field of reproductive medicine. The first clinical programs were established to preserve reproductive potential in men needing gonadotoxic treatment. Sperm cryopreservation is now a standard procedure. Since a few years, several centres offer testicular tissue cryopreservation to prepubertal boys. This method is still experimental and further research is needed to implement the transplantation techniques in the clinic. With the aim to preserve or restore fertility in patients affected by other diseases (Klinefelter syndrome, Sertoli cell only syndrome), techniques for in vitro spermatogenesis are being developed.
男性生育力保存在生殖医学领域受到越来越多的关注。首个临床项目旨在为需要接受性腺毒性治疗的男性保留生殖潜能。精子冷冻保存如今已是标准程序。近年来,多个中心为青春期前男孩提供睾丸组织冷冻保存服务。该方法仍处于实验阶段,需要进一步研究以便在临床中应用移植技术。为了在受其他疾病(克兰费尔特综合征、唯支持细胞综合征)影响的患者中保存或恢复生育力,体外精子发生技术正在研发中。