Cecio A, Vittoria A
Department of Biological Structures, Functions and Technology, University of Naples, Italy.
Arch Histol Cytol. 1989;52 Suppl:403-13. doi: 10.1679/aohc.52.suppl_403.
Amines and/or peptide-producing cells, deserving to be called paraneurons, were demonstrated in the urethro-prostatic complex of the man, rabbit, buffalo and sheep and in the uterine horns of the pig, horse and mouse, by means of histochemical, immunohistochemical, immunofluorescent and double labeling immunofluorescent techniques. In particular, the urethro-prostatic complex of the sheep contains cells producing serotonin, chromogranin A and somatostatin. Often the amine and the "marker"-protein were colocalized in the same cells. Chromogranin A- and somatostatin-containing cells were found in the uterine horns of the pig. Serotonin probably plays a role in the contraction/relaxation of the musculature of the male urogenital tract, thus regulating the urinary and spermatic flow. The function of somatostatin cells in the urogenital tract is unknown. The presence and direction of their cytoplasmic processes lead us to hypothesize a double endocrine/paracrine modality of action.
通过组织化学、免疫组织化学、免疫荧光和双标记免疫荧光技术，在男性、兔子、水牛和绵羊的尿道前列腺复合体以及猪、马和小鼠的子宫角中，证实了产生胺类和/或肽类的细胞，它们堪称副神经元。特别地，绵羊的尿道前列腺复合体含有产生5-羟色胺、嗜铬粒蛋白A和生长抑素的细胞。胺类和“标记”蛋白常常共定位于同一细胞中。在猪的子宫角中发现了含嗜铬粒蛋白A和生长抑素的细胞。5-羟色胺可能在男性泌尿生殖道肌肉组织的收缩/舒张中发挥作用，从而调节尿液和精液的排出。泌尿生殖道中生长抑素细胞的功能尚不清楚。它们细胞质突起的存在和方向使我们推测其作用方式为双内分泌/旁分泌模式。
