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口服氯化钡中毒病例中通过电感耦合等离子体质谱法测定胃内容物、血液和尿液中的钡含量。

Barium determination in gastric contents, blood and urine by inductively coupled plasma mass spectrometry in the case of oral barium chloride poisoning.

作者信息

Łukasik-Głębocka Magdalena, Sommerfeld Karina, Hanć Anetta, Grzegorowski Adam, Barałkiewicz Danuta, Gaca Michał, Zielińska-Psuja Barbara

机构信息

Department of Emergency Medicine, Poznan University of Medical Sciences, Poland Department of Toxicology, Raszeja Hospital, Poznań, Poland.

Department of Toxicology, Poznan University of Medical Sciences, Poland

出版信息

J Anal Toxicol. 2014 Jul-Aug;38(6):380-2. doi: 10.1093/jat/bku037. Epub 2014 May 2.

Abstract

A serious case of barium intoxication from suicidal ingestion is reported. Oral barium chloride poisoning with hypokalemia, neuromuscular and cardiac toxicity, treated with intravenous potassium supplementation and hemodialysis, was confirmed by the determination of barium concentrations in gastric contents, blood, serum and urine using the inductively coupled plasma mass spectrometry method. Barium concentrations in the analyzed specimens were 20.45 µg/L in serum, 150 µg/L in blood, 10,500 µg/L in urine and 63,500 µg/L in gastric contents. Results were compared with barium levels obtained from a non-intoxicated person.

摘要

报告了一例因自杀性摄入钡剂导致的严重中毒病例。通过电感耦合等离子体质谱法测定胃内容物、血液、血清和尿液中的钡浓度,确诊为口服氯化钡中毒伴低钾血症、神经肌肉和心脏毒性,采用静脉补充钾和血液透析进行治疗。分析标本中的钡浓度分别为:血清20.45µg/L、血液150µg/L、尿液10500µg/L、胃内容物63500µg/L。将结果与一名未中毒者的钡水平进行了比较。

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