Tanaka T, Hara K, Tanimoto A, Kasai K, Kita T, Tanaka N, Takayasu T
Department of Forensic Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Forensic Sci Int. 1996 Jul 31;81(1):43-50. doi: 10.1016/0379-0738(96)01942-1.
Inductively coupled plasma/mass spectrometry (ICP/MS) was used and evaluated for the practical analysis of the arsenic content of body fluid samples without ashing. The calibration curve for arsenic in blood solution was shown to have good sensitivity, linearity and reproducibility. Blood obtained from normal volunteers was determined by ICP/MS, and compared with that determined by atomic absorption spectrometry (AAS). The arsenic contents determined by ICP/MS showed a linear correlation with that determined by AAS. Furthermore, arsenic was determined in the blood and supernatant of stomach contents obtained from a suicide autopsy case resulting from ingestion of an arsenic compound. It was therefore concluded that ICP/MS could be used rapidly and conveniently in the field of forensic toxicology in acute metal poisoning cases.
采用电感耦合等离子体质谱法（ICP/MS）对未经灰化的体液样本中的砷含量进行实际分析并评估。结果表明，血液溶液中砷的校准曲线具有良好的灵敏度、线性和重现性。采用ICP/MS对正常志愿者的血液进行检测，并与原子吸收光谱法（AAS）的检测结果进行比较。ICP/MS测定的砷含量与AAS测定的结果呈线性相关。此外，对一例因摄入砷化合物自杀尸检病例的血液和胃内容物上清液中的砷进行了测定。因此得出结论，在急性金属中毒案件的法医毒理学领域，ICP/MS可快速、便捷地使用。
