• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

不可思议的低钾血症:一例急性重度氯化钡中毒病例报告

Inconceivable Hypokalemia: A Case Report of Acute Severe Barium Chloride Poisoning.

作者信息

Tao Haibo, Man Yanru, Shi Xiaoyuan, Zhu Jun, Pan Hang, Qin Qin, Liu Shanrong

机构信息

Department of Clinical Laboratory, Changhai Hospital, The Second Military Medical University, Shanghai 200433, China.

出版信息

Case Rep Med. 2016;2016:2743134. doi: 10.1155/2016/2743134. Epub 2016 Oct 20.

DOI:10.1155/2016/2743134
PMID:27840643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5093257/
Abstract

Barium is a heavy divalent alkaline earth metal that has been known as a muscle poison. Barium can cause human toxicity, which may lead to significant hypokalemia and have serious consequences. This paper reports a case of unprecedented barium intoxication in which the patient, who suffered from depression, swallowed at least 3.0 g barium chloride to commit suicide. On admission, the patient presented with nausea, vomiting, stomach burning feeling, dizziness, and weakness. Emergency biochemical testing showed that the patient was suffering from severe hypokalemia (K 1.7 mmol/L). His electrocardiogram (ECG) prompted atrioventricular blocking, ventricular tachycardia, prolongation of PR interval, ST segment depression with U waves, and T wave inversion. Intravenous potassium supplements were given immediately to correct hypokalemia and regular monitoring of vital signs and fluid balance was arranged. After all-out rescue of our hospital personnel, the condition of the patient is currently stable and he is gradually recovering. This case exemplifies the weaknesses of the management of toxic substances and the lack of mental health education for young people. We hope to get more attention for the supervision of toxic substances and the healthy development of young people.

摘要

钡是一种重的二价碱土金属,一直被认为是一种肌肉毒素。钡可导致人体中毒,可能会引发严重的低钾血症并产生严重后果。本文报告了一例前所未有的钡中毒病例,该患者患有抑郁症,吞服了至少3.0克氯化钡以自杀。入院时,患者出现恶心、呕吐、胃部烧灼感、头晕和虚弱症状。紧急生化检查显示患者患有严重低钾血症(血钾1.7毫摩尔/升)。他的心电图提示房室传导阻滞、室性心动过速、PR间期延长、ST段压低伴U波以及T波倒置。立即给予静脉补钾以纠正低钾血症,并安排定期监测生命体征和液体平衡。经过我院医护人员的全力抢救,患者目前病情稳定,正在逐渐康复。该病例体现了有毒物质管理方面的薄弱环节以及对年轻人心理健康教育的缺失。我们希望能引起对有毒物质监管和年轻人健康发展的更多关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffdf/5093257/3a8e189c91a5/CRIM2016-2743134.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffdf/5093257/3a8e189c91a5/CRIM2016-2743134.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffdf/5093257/3a8e189c91a5/CRIM2016-2743134.001.jpg

相似文献

1
Inconceivable Hypokalemia: A Case Report of Acute Severe Barium Chloride Poisoning.不可思议的低钾血症:一例急性重度氯化钡中毒病例报告
Case Rep Med. 2016;2016:2743134. doi: 10.1155/2016/2743134. Epub 2016 Oct 20.
2
Rare electrocardiographic findings in a young woman with acute barium poisoning: A case report.一名年轻女性急性钡中毒的罕见心电图表现:病例报告
Heliyon. 2024 Aug 29;10(17):e37136. doi: 10.1016/j.heliyon.2024.e37136. eCollection 2024 Sep 15.
3
Barium toxicity and the role of the potassium inward rectifier current.钡毒性与钾内向整流电流的作用。
Clin Toxicol (Phila). 2014 Jul;52(6):584-93. doi: 10.3109/15563650.2014.923903. Epub 2014 Jun 6.
4
[Barium intoxication: a case report].[钡中毒:一例报告]
J Formos Med Assoc. 1991 Sep;90(9):908-10.
5
Mass barium carbonate poisoning with fatal outcome, lessons learned: a case series.碳酸钡群体中毒致死亡结局:经验教训——病例系列报道
Cases J. 2009 Dec 16;2:9327. doi: 10.1186/1757-1626-2-9327.
6
Mass barium carbonate poisoning with fatal outcome, lessons learned: a case series.重度碳酸钡中毒致死亡病例系列及经验教训
Cases J. 2009 Sep 1;2:9069. doi: 10.1186/1757-1626-0002-0000009069.
7
Disturbances of potassium homeostasis in poisoning.中毒时钾稳态的紊乱
J Toxicol Clin Toxicol. 1995;33(4):295-310. doi: 10.3109/15563659509028915.
8
Acute barium poisoning in a dog after ingestion of handheld fireworks (party sparklers).一只狗因误食手持烟花(派对烟火棒)后发生急性钡中毒。
J Vet Emerg Crit Care (San Antonio). 2019 Mar;29(2):201-207. doi: 10.1111/vec.12820. Epub 2019 Mar 12.
9
Acute barium nitrate intoxication treated by hemodialysis.血液透析治疗急性硝酸钡中毒
Acta Anaesthesiol Scand. 2005 Jan;49(1):110-2. doi: 10.1111/j.1399-6576.2005.00488.x.
10
The essential role of a poison center in handling an outbreak of barium carbonate poisoning.毒物中心在处理碳酸钡中毒疫情中的重要作用。
Vet Hum Toxicol. 1991 Apr;33(2):173-5.

引用本文的文献

1
Review of the Pathophysiologic and Clinical Aspects of Hypokalemia in Children and Young Adults: an Update.儿童和青年低钾血症的病理生理及临床方面综述:最新进展
Curr Treat Options Pediatr. 2022;8(3):96-114. doi: 10.1007/s40746-022-00240-3. Epub 2022 May 18.
2
Mixture Toxicity of Three Unconventional Gas Fracking Chemicals, Barium, O-Cresol, and Sodium Chloride, to the Freshwater Shrimp Paratya australiensis.三种非常规天然气压裂化学品(钡、邻甲酚和氯化钠)混合物对南方沼虾的毒性。
Environ Toxicol Chem. 2023 Feb;42(2):481-494. doi: 10.1002/etc.5538. Epub 2023 Jan 13.
3
Human Health Risk Assessment of Heavy Metals and Metalloids in Herbal Medicines Used to Treat Anxiety: Monitoring of Safety.

本文引用的文献

1
ECG Case of the Month: Unexpected Atrioventricular Conduction in High-Grade Atrioventricular Block. Sinus rhythm; high-grade second degree atrioventricular block with a junctional escape rhythm and three capture complexes, each with right bundle branch block aberration; possible septal myocardial infarct of indeterminate age; ST-T and U wave changes suggesting hypokalemia.本月心电图病例:高度房室传导阻滞中的意外房室传导。窦性心律;高度二度房室传导阻滞伴交界性逸搏心律及三个夺获心搏,每个夺获心搏均伴有右束支传导阻滞差异;可能为年龄不确定的间隔心肌梗死;ST-T段及U波改变提示低钾血症。
J La State Med Soc. 2015 Mar-Apr;167(2):97-9. Epub 2015 Apr 15.
2
Incorrigible hypokalemia caused by barium chloride ingestion.因摄入氯化钡导致的顽固性低钾血症。
Am J Med Sci. 2015 Mar;349(3):279-81. doi: 10.1097/MAJ.0000000000000375.
3
用于治疗焦虑症的草药中重金属和类金属的人体健康风险评估:安全性监测
Front Pharmacol. 2021 Nov 10;12:772928. doi: 10.3389/fphar.2021.772928. eCollection 2021.
4
Hypokalaemic paralysis as the initial clinical presentation of Sjogren's syndrome induced distal renal tubular acidosis.低钾性麻痹作为干燥综合征诱发的远端肾小管酸中毒的初始临床表现。
BMJ Case Rep. 2021 May 6;14(5):e241300. doi: 10.1136/bcr-2020-241300.
5
Prenatal metal mixtures and sex-specific infant negative affectivity.产前金属混合物与婴儿特定性别的消极情感
Environ Epidemiol. 2021 Apr 2;5(2):e147. doi: 10.1097/EE9.0000000000000147. eCollection 2021 Apr.
Barium toxicity and the role of the potassium inward rectifier current.钡毒性与钾内向整流电流的作用。
Clin Toxicol (Phila). 2014 Jul;52(6):584-93. doi: 10.3109/15563650.2014.923903. Epub 2014 Jun 6.
4
Barium determination in gastric contents, blood and urine by inductively coupled plasma mass spectrometry in the case of oral barium chloride poisoning.口服氯化钡中毒病例中通过电感耦合等离子体质谱法测定胃内容物、血液和尿液中的钡含量。
J Anal Toxicol. 2014 Jul-Aug;38(6):380-2. doi: 10.1093/jat/bku037. Epub 2014 May 2.
5
Fatal barium chloride poisoning: four cases report and literature review.致命性氯化钡中毒:4例报告及文献复习
Am J Forensic Med Pathol. 2013 Jun;34(2):115-8. doi: 10.1097/PAF.0b013e31828a2626.
6
Acute barium intoxication following ingestion of soap water solution.摄入肥皂水后发生急性钡中毒。
Indian J Crit Care Med. 2012 Oct;16(4):238-40. doi: 10.4103/0972-5229.106513.
7
Acute barium intoxication following accidental inhalation of barium chloride.意外吸入氯化钡后发生的急性钡中毒
Intern Med J. 2011 Mar;41(3):293-5. doi: 10.1111/j.1445-5994.2011.02424.x.
8
Elementary, my dear Dr. Allen: the case of barium toxicity and Pa Ping.小儿科,亲爱的艾伦医生:钡中毒和怕平案。
Neurology. 2010 May 11;74(19):1546-9. doi: 10.1212/WNL.0b013e3181e222ee.
9
Mass barium carbonate poisoning with fatal outcome, lessons learned: a case series.碳酸钡群体中毒致死亡结局:经验教训——病例系列报道
Cases J. 2009 Dec 16;2:9327. doi: 10.1186/1757-1626-2-9327.
10
Paradoxical depolarization of BA2+- treated muscle exposed to low extracellular K+: insights into resting potential abnormalities in hypokalemic paralysis.暴露于低细胞外钾的Ba2+处理肌肉的反常去极化:对低钾性麻痹静息电位异常的见解。
Muscle Nerve. 2008 Mar;37(3):326-37. doi: 10.1002/mus.20928.