Bahadur Shalini, Sethi Neha, Pahuja Sangeeta, Pathak Chintamani, Jain Manjula
Department of Pathology and Blood Bank, Lady Hardinge Medical College, New Delhi, India.
Indian J Pediatr. 2015 Apr;82(4):333-9. doi: 10.1007/s12098-014-1370-2. Epub 2014 May 3.
To perform a retrospective audit of transfusion practices, in order to study the appropriate and inappropriate usage of different blood components in pediatric population.
The present study, conducted over a period of 3 mo analyzed all the episodes of transfusions and divided them into appropriate and inappropriate according to the type of blood components, the requesting departments and the clinical indication of transfusion. Data was reviewed according to the British Committee for Standards in Hematology and American Association of Blood Bank guidelines.
A total of 2,145 units of hemocomponents were transfused to children, including 1,181 units of red cell concentrates, 566 units of platelet concentrates/platelet rich plasma, 118 units of whole blood and 280 units of fresh frozen plasma in 1,819 episodes. Appropriate usage of blood components was 59.65%. Whole blood was most appropriately transfused (82.9%). Appropriate indications outnumbered inappropriate requisitions in Department of Pediatric Medicine (70.38 %), Nursery (82.54 %) and Thalassemia day care centre (55.63%). Red cell concentrate was most appropriately indicated in anemias (73.14%) and inappropriately in cases of surgeries (53.6%). Platelets were used more appropriately in all clinical indications. Whole blood was transfused most appropriately (100%) in double venous exchange therapy. Most appropriate indication of fresh frozen plasma usage was coagulopathy (42.57%).
As the appropriate usage (59.65%) of blood components was low in the present study, regular auditing of transfusion practices from time to time is indicated. This not only helps guide their judicious use but also serves to evaluate and decrease their inappropriate usage.
对输血实践进行回顾性审核,以研究儿科人群中不同血液成分的合理与不合理使用情况。
本研究在3个月的时间内进行,分析了所有输血事件,并根据血液成分类型、申请科室和输血临床指征将其分为合理和不合理两类。数据根据英国血液学标准委员会和美国血库协会的指南进行审查。
共向儿童输注了2145单位血液成分,包括1819次输血事件中的1181单位红细胞浓缩液、566单位血小板浓缩液/富血小板血浆、118单位全血和280单位新鲜冰冻血浆。血液成分的合理使用率为59.65%。全血的输注最为合理(82.9%)。儿科、新生儿室和地中海贫血日间护理中心的合理指征数量超过不合理申请数量(分别为70.38%、82.54%和55.63%)。红细胞浓缩液在贫血中使用最为合理(73.14%),而在手术病例中使用不当(53.6%)。血小板在所有临床指征中的使用更为合理。全血在双静脉交换治疗中输注最为合理(100%)。新鲜冰冻血浆使用的最合理指征是凝血病(42.57%)。
由于本研究中血液成分的合理使用率较低(59.65%),因此建议定期对输血实践进行审核。这不仅有助于指导其合理使用,还可用于评估和减少其不合理使用。