Farshidpanah S, Klein W, Matus M, Sai A, Nguyen H B
Division of Pulmonary and Critical Care, Loma Linda University, Loma Linda, California, USA.
Anaesth Intensive Care. 2014 May;42(3):321-9. doi: 10.1177/0310057X1404200308.
Assessing intravascular volume status in the critically ill patient remains a challenge for intensivists, and the accuracy of such estimation based on bedside examination alone is reported to be nearly a coin toss. In this retrospective study we sought to validate a previously recommended chest radiographic vascular pedicle width (VPW) ≥70 mm for identifying cardiogenic pulmonary oedema (CPO). We additionally assessed whether novice physicians-in-training can reliably measure the VPW. The study included intensive care patients with an existing pulmonary artery catheter. Three independent raters performed measurements of VPW from chest radiographs obtained within three hours of pulmonary artery occlusion pressure measurements. In 80 patients enrolled, a VPW cut-off of ≥70 mm had a 55% sensitivity, 88% specificity, 81% positive predictive value, 69% negative predictive value and 73% accuracy for identifying patients with CPO. Receiver operating characteristic curve analysis showed an area under the curve of 0.72 (95% confidence interval 0.61 to 0.84) for VPW in discriminating CPO from non-cardiogenic pulmonary oedema. Kappa statistics for inter-rater reliability showed Kappa=0.41, 0.42 and 0.85 for each pair of the three raters. In conclusion, the previously accepted VPW cut-off of ≥70 mm is reasonably accurate in discriminating CPO from non-cardiogenic pulmonary oedema. VPW can be measured by physicians-in-training with a comparable performance to previous studies utilising expert radiologists.
评估重症患者的血管内容量状态对重症监护医生来说仍是一项挑战,据报道,仅基于床边检查进行此类评估的准确性几乎是碰运气。在这项回顾性研究中,我们试图验证先前推荐的胸部X线血管蒂宽度(VPW)≥70 mm用于识别心源性肺水肿(CPO)的有效性。我们还评估了实习医生能否可靠地测量VPW。该研究纳入了有肺动脉导管的重症监护患者。三名独立评估者对在肺动脉闭塞压测量后三小时内获得的胸部X线片进行VPW测量。在纳入的80例患者中,VPW截断值≥70 mm识别CPO患者的灵敏度为55%,特异度为88%,阳性预测值为81%,阴性预测值为69%,准确率为73%。受试者工作特征曲线分析显示,VPW在区分CPO和非心源性肺水肿方面的曲线下面积为0.72(95%置信区间0.61至0.84)。三名评估者两两之间的评分者间信度的Kappa统计值分别为0.41、0.42和0.85。总之,先前接受的VPW截断值≥70 mm在区分CPO和非心源性肺水肿方面具有合理的准确性。实习医生可以测量VPW,其表现与先前利用专家放射科医生的研究相当。