Vince John David, Datta Siddhartha Sankar, Toikilik Steven, Lagani William
School of Medicine and Health Sciences, University of Papua New Guinea, Papua New Guinea.
Expanded Programme on Immunization, World Health Organisation, Papua New Guinea.
Vaccine. 2014 Aug 6;32(36):4614-9. doi: 10.1016/j.vaccine.2014.04.056. Epub 2014 Apr 30.
Papua New Guinea's difficult and varied topography, poor transport infrastructure, changing dynamics of population and economy in recent times and understaffed and poorly financed health service present major challenges for successful delivery of vaccination and other preventative health interventions to both the rural majority and urban populations, thereby posing risks for vaccine preventable disease outbreaks in the country. The country has struggled to meet the vaccination coverage targets required for the eradication of poliomyelitis and elimination of measles. Escalation of inter and intra country migration resulting from major industrial developments, particularly in extraction industries, has substantially increased the risk of infectious disease importation. This case study documents the evolution of immunisation programmes since the introduction of supplementary immunisation activities (SIAs). Single antigen SIAs have advantages and disadvantages. In situations in which the delivery of preventative health interventions is difficult, it is likely that the cost benefit is greater for multiple than for single intervention. The lessons learned from the conduct of single antigen SIAs can be effectively used for programmes delivering multiple SIA antigens, routine immunisations, and other health interventions. This paper describes a successful and cost effective multiple intervention programme in Papua New Guinea. The review of the last SIA in Papua New Guinea showed relatively high coverage of all the interventions and demonstrated the operational feasibility of delivering multiple interventions in resource constrained settings. Studies in other developing countries such as Lesotho and Ethiopia have also successfully integrated health interventions with SIA. In settings such as Papua New Guinea there is a strong case for integrating supplementary immunisation activity with routine immunisation and other health interventions through a comprehensive outreach programme.
巴布亚新几内亚地形复杂多样,交通基础设施薄弱,近年来人口与经济动态不断变化,卫生服务人员配备不足且资金匮乏,这给成功向广大农村和城市人口提供疫苗接种及其他预防性卫生干预措施带来了重大挑战,从而使该国面临疫苗可预防疾病暴发的风险。该国一直难以实现根除脊髓灰质炎和消除麻疹所需的疫苗接种覆盖率目标。主要工业发展,特别是采掘业发展导致的国内和国家间移民增加,大幅提高了传染病输入风险。本案例研究记录了自引入补充免疫活动(SIAs)以来免疫规划的演变。单一抗原SIAs有其优缺点。在提供预防性卫生干预措施困难的情况下,多项干预措施的成本效益可能高于单一干预措施。从单一抗原SIAs实施中吸取的经验教训可有效用于提供多种SIA抗原、常规免疫接种及其他卫生干预措施的项目。本文描述了巴布亚新几内亚一个成功且具有成本效益的多项干预项目。对巴布亚新几内亚上一次SIA的审查显示,所有干预措施的覆盖率相对较高,并证明了在资源有限的环境中提供多项干预措施的操作可行性。莱索托和埃塞俄比亚等其他发展中国家的研究也成功地将卫生干预措施与SIA相结合。在巴布亚新几内亚这样的环境中,通过全面的外展项目将补充免疫活动与常规免疫接种及其他卫生干预措施相结合很有必要。