Susantitaphong Paweena, Eiam-Ong Somchai
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok 10330, Thailand ; Extracorporeal Multiorgan Support Dialysis Center, Division of Nephrology, Department of Medicine, King Chulalongkorn Memorial Hospital, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok 10330, Thailand.
Biomed Res Int. 2014;2014:463608. doi: 10.1155/2014/463608. Epub 2014 Mar 26.
Contrast-induced AKI (CI-AKI) has been one of the leading causes for hospital-acquired AKI and is associated with independent risk for adverse clinical outcomes including morbidity and mortality. The aim of this review is to provide a brief summary of the studies that focus on nonpharmacological strategies to prevent CI-AKI, including routine identification of at-risk patients, use of appropriate hydration regimens, withdrawal of nephrotoxic drugs, selection of low-osmolar contrast media or isoosmolar contrast media, and using the minimum volume of contrast media as possible. There is no need to schedule dialysis in relation to injection of contrast media or injection of contrast agent in relation to dialysis program. Hemodialysis cannot protect the poorly functioning kidney against CI-AKI.
对比剂诱导的急性肾损伤(CI-AKI)一直是医院获得性急性肾损伤的主要原因之一,并且与包括发病率和死亡率在内的不良临床结局的独立风险相关。本综述的目的是简要总结专注于预防CI-AKI的非药物策略的研究,包括对高危患者的常规识别、使用适当的水化方案、停用肾毒性药物、选择低渗对比剂或等渗对比剂以及尽可能使用最小剂量的对比剂。无需根据对比剂注射安排透析,也无需根据透析计划注射对比剂。血液透析不能保护功能不佳的肾脏免受CI-AKI的影响。