Nagai Michiaki, Kario Kazuomi
Nihon Rinsho. 2014 Apr;72(4):715-20.
Recent studies have shown that ischemic heart disease and heart failure are closely associated with cognitive impairment via injury of the small cerebral arteries. On the other hand, these factors are suggested to be associated with Alzheimer's disease as well as vascular dementia. This review paper focuses on the role of ischemic heart disease and heart failure as risk factors for cognitive impairment, and summarizes current knowledge on the relationships between vascular risk factors and Alzheimer's disease pathology.
最近的研究表明,缺血性心脏病和心力衰竭通过损伤脑小动脉与认知障碍密切相关。另一方面,这些因素被认为与阿尔茨海默病以及血管性痴呆有关。这篇综述文章重点关注缺血性心脏病和心力衰竭作为认知障碍危险因素的作用,并总结了目前关于血管危险因素与阿尔茨海默病病理学之间关系的知识。