Netcare Linksfield Orthopaedic Sports & Rehabilitation Centre (Clinic), Johannesburg, South Africa; Orthopaedic Department, University of the Witwatersrand, Johannesburg, South Africa.
Department of Molecular Medicine and Haematology, School of Pathology, Faculty of Health Sciences of the University of the Witwatersrand, National Health Laboratory Services, Johannesburg, South Africa.
Foot Ankle Surg. 2014 Jun;20(2):85-9. doi: 10.1016/j.fas.2013.11.002. Epub 2013 Nov 14.
The purpose of this prospective study was to determine whether the more frequently quoted procedure and patient specific risk factors have any impact in the implementation of venous thromboembolism (VTE) prophylaxis following foot and ankle surgery.
Two hundred and sixteen patients were included in the study. A variety of operative procedures was carried out with the common denominator being a below knee cast for at least 4 weeks and nonweightbearing for an average of 6 weeks in 130 patients. The remainder of the patients (88) had hallux surgery not requiring a cast and were allowed to weightbear. No patient received any form of thromboprophylaxis postoperatively. All patients were subjected to compression ultrasonography for deep vein thrombosis (DVT) between 2 and 6 weeks postoperatively.
There was a 5.09% incidence of VTE (0.9% pulmonary embolism) overall. As no VTE (neither DVT nor pulmonary embolus) developed in the hallux subgroup, i.e. patients not requiring immobilization and were allowed to weightbear, the incidence of VTE in the cast/nonweightbearing group was 8.46%. The results are descriptive and only statistically analyzed where possible, as the sample size of the VTE group was small. There was no significant difference in number of risk factors and no association between gender in the VTE and non VTE groups. 90.9% of patients in the VTE group had a total risk factor score of 5 or more and 73.7% of patients in the non VTE group had a total risk factor score of 5 or more. The average timing to the diagnosis of VTE in this current study was 33.1 days.
In view of the unacceptable incidence of VTE and the average total risk factor score of 5 or more (for which thromboprophylaxis is recommended) in the majority of the patients, the authors feel that the routine use of thromboprophylaxis in foot and ankle surgery requiring nonweightbearing in combination with short leg cast immobilization, is warranted. This prophylaxis should continue until the patient regains adequate mobility either by weightbearing (in or out of the cast) or removal of cast immobilization (weightbearing or nonweightbearing), usually between 28 and 42 days.
本前瞻性研究旨在确定更为频繁引用的手术和患者特定风险因素是否会影响足踝手术后静脉血栓栓塞症(VTE)的预防措施实施。
本研究纳入了 216 名患者。实施了各种手术,共同特征为至少 4 周的膝下石膏固定和 130 名患者平均 6 周的非负重。其余 88 名患者(行拇趾手术,无需石膏固定,可负重)。所有患者术后均未接受任何形式的血栓预防治疗。所有患者术后 2-6 周均行下肢深静脉超声检查。
总体 VTE 发生率为 5.09%(0.9%为肺栓塞)。由于拇趾亚组(无需固定且允许负重)无 VTE(无深静脉血栓形成或肺栓塞)发生,即无需固定且允许负重的患者,石膏固定/非负重组的 VTE 发生率为 8.46%。结果仅作描述性分析,仅在可能的情况下进行统计学分析,因为 VTE 组的样本量较小。VTE 组和非 VTE 组的风险因素数量无显著差异,且性别无关联。VTE 组 90.9%的患者总风险因素评分为 5 分或以上,而非 VTE 组 73.7%的患者总风险因素评分为 5 分或以上。本研究中 VTE 的平均确诊时间为 33.1 天。
鉴于 VTE 的不可接受发生率以及大多数患者的平均总风险因素评分 5 分或以上(推荐使用血栓预防治疗),作者认为对于需要非负重结合短腿石膏固定的足踝手术,常规使用血栓预防治疗是合理的。该预防治疗应持续至患者恢复足够的活动能力,无论是通过负重(石膏内或外)还是去除石膏固定(负重或非负重),通常在 28-42 天。