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在一家城市三级医疗健康安全网医院中,比较Caprini评分与一种机构风险评估工具对全关节置换术后静脉血栓栓塞的预测能力。

A Comparison of the Caprini Score With an Institutional Risk Assessment Tool for Prediction of Venous Thromboembolism After Total Joint Arthroplasty at an Urban Tertiary Care Health Safety Net Hospital.

作者信息

Gibbs Brian, Paek Samuel, Wojciechowski Noelle, Wrenn Sean, Freccero David M, Abdeen Ayesha

机构信息

Department of Orthopaedic Surgery, Boston Medical Center, Boston, MA, USA.

Geisinger Commonwealth School of Medicine, Scranton, PA, USA.

出版信息

Arthroplast Today. 2023 Sep 19;23:101194. doi: 10.1016/j.artd.2023.101194. eCollection 2023 Oct.

Abstract

BACKGROUND

Patients undergoing total joint arthroplasty (TJA) are at increased risk for venous thromboembolism (VTE). Prediction tools such as the Caprini Risk Assessment Model (RAM) have been developed to identify patients at higher risk. However, studies have reported heterogeneous results when assessing its efficacy for TJA. Patients treated in an urban health safety net hospital have increased medical complexity, advanced degenerative joint disease, and severe disability prior to TJA increasing the risk of VTE. We hypothesize that use of a tool designed to account for these conditions-the Boston Medical Center (BMC) VTE score-will more accurately predict VTE in this patient population.

METHODS

A retrospective case-control study was performed including subjects 18 years of age and older who underwent primary or revision TJA in an urban academic health safety net hospital. Patients with hemiarthroplasties, simultaneous bilateral TJA, and TJA after acute trauma were excluded. A total of 80 subjects were included: 40 who developed VTE after TJA (VTE+) and 40 who did not develop VTE (controls). Subjects were matched by age, gender, and surgical procedure.

RESULTS

There was a statistically significant difference between the mean BMC VTE score for VTE+ and controls (4.40 and 3.13, respectively, = .036). Conversely, there was no statistical difference between the mean Caprini scores for VTE+ and controls (9.50 and 9.35, respectively, = .797).

CONCLUSIONS

In a health safety-net patient population, an institutional RAM-the BMC VTE score-was found to be more predictive of VTE than the modified Caprini RAM following TJA. The BMC-VTE score should be externally validated to confirm its reliability in VTE prediction in similar patient populations.

摘要

背景

接受全关节置换术(TJA)的患者发生静脉血栓栓塞症(VTE)的风险增加。已开发出如Caprini风险评估模型(RAM)等预测工具来识别高危患者。然而,在评估其对TJA的有效性时,研究报告的结果存在异质性。在城市健康安全网医院接受治疗的患者在TJA之前存在医疗复杂性增加、晚期退行性关节疾病和严重残疾的情况,这增加了VTE的风险。我们假设,使用一种旨在考虑这些情况的工具——波士顿医疗中心(BMC)VTE评分——将能更准确地预测该患者群体中的VTE。

方法

进行了一项回顾性病例对照研究,纳入在城市学术健康安全网医院接受初次或翻修TJA的18岁及以上患者。排除接受半关节置换术、同期双侧TJA以及急性创伤后TJA的患者。共纳入80名受试者:40名在TJA后发生VTE的患者(VTE+组)和40名未发生VTE的患者(对照组)。受试者按年龄、性别和手术方式进行匹配。

结果

VTE+组和对照组的平均BMC VTE评分之间存在统计学显著差异(分别为4.40和3.13,P = .036)。相反,VTE+组和对照组的平均Caprini评分之间无统计学差异(分别为9.50和9.35,P = .797)。

结论

在健康安全网患者群体中,发现一种机构性RAM——BMC VTE评分——比TJA后改良的Caprini RAM更能预测VTE。BMC - VTE评分应进行外部验证,以确认其在类似患者群体中预测VTE的可靠性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9b2/10517285/744268e14e78/gr1.jpg

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