Tan Lianjiang, Wan Ajun, Zhao Tingting, Huang Ran, Li Huili
School of Chemistry and Chemical Engineering and §School of Pharmacy, Shanghai Jiao Tong University , Shanghai 200240, China.
ACS Appl Mater Interfaces. 2014 May 14;6(9):6217-22. doi: 10.1021/am5015088. Epub 2014 May 5.
A new strategy for fabricating water-dispersible Ag2Se quantum dots (QDs) is presented. A multidentate polymer (MDP) was synthesized and used as a capping agent for Ag2Se QDs. The MDP-capping Ag2Se QDs were synthesized in aqueous solution at room temperature, which are highly photoluminescent in a second near-infrared (NIR-II) biological window and possess good photostability. These readily prepared NIR-II fluorescent nanoprobes have great potential for biomedical applications, especially useful for in vivo imaging.
提出了一种制备水分散性Ag2Se量子点(QDs)的新策略。合成了一种多齿聚合物(MDP)并将其用作Ag2Se量子点的封端剂。MDP封端的Ag2Se量子点在室温下于水溶液中合成,在第二近红外(NIR-II)生物窗口中具有高发光性且具有良好的光稳定性。这些易于制备的NIR-II荧光纳米探针在生物医学应用中具有巨大潜力,尤其适用于体内成像。