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在第二近红外生物窗口中具有明亮且可光致发光调谐的多齿聚合物包覆Ag2Se量子点的水相合成。

Aqueous synthesis of multidentate-polymer-capping Ag2Se quantum dots with bright photoluminescence tunable in a second near-infrared biological window.

作者信息

Tan Lianjiang, Wan Ajun, Zhao Tingting, Huang Ran, Li Huili

机构信息

School of Chemistry and Chemical Engineering and §School of Pharmacy, Shanghai Jiao Tong University , Shanghai 200240, China.

出版信息

ACS Appl Mater Interfaces. 2014 May 14;6(9):6217-22. doi: 10.1021/am5015088. Epub 2014 May 5.

Abstract

A new strategy for fabricating water-dispersible Ag2Se quantum dots (QDs) is presented. A multidentate polymer (MDP) was synthesized and used as a capping agent for Ag2Se QDs. The MDP-capping Ag2Se QDs were synthesized in aqueous solution at room temperature, which are highly photoluminescent in a second near-infrared (NIR-II) biological window and possess good photostability. These readily prepared NIR-II fluorescent nanoprobes have great potential for biomedical applications, especially useful for in vivo imaging.

摘要

提出了一种制备水分散性Ag2Se量子点(QDs)的新策略。合成了一种多齿聚合物(MDP)并将其用作Ag2Se量子点的封端剂。MDP封端的Ag2Se量子点在室温下于水溶液中合成,在第二近红外(NIR-II)生物窗口中具有高发光性且具有良好的光稳定性。这些易于制备的NIR-II荧光纳米探针在生物医学应用中具有巨大潜力,尤其适用于体内成像。

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