Chinnathambi Shanmugavel, Shirahata Naoto
International Center for Young Scientists, National Institute for Materials Science (NIMS), Tsukuba, Japan.
International Center for Materials Nanoarchitectonics, NIMS, Tsukuba, Japan.
Sci Technol Adv Mater. 2019 Apr 15;20(1):337-355. doi: 10.1080/14686996.2019.1590731. eCollection 2019.
Luminescence probe has been broadly used for bio-imaging applications. Among them, near-infrared (NIR) quantum dots (QDs) are more attractive due to minimal tissue absorbance and larger penetration depth. Above said reasons allowed whole animal imaging without slice scan or dissection. This review describes and imaging of NIR QDs in the regions of 650-900 nm (NIR-I) and 1000-1450 nm (NIR-II). Also, we summarize the recent progress in bio-imaging and discuss the future trends of NIR QDs including group II-VI, IV-VI, I-VI, I-III-VI, III-V, and IV semiconductors.
发光探针已广泛应用于生物成像领域。其中，近红外（NIR）量子点（QDs）因其最小的组织吸收率和更大的穿透深度而更具吸引力。基于上述原因，无需切片扫描或解剖即可进行全动物成像。本综述描述了650-900nm（近红外一区）和1000-1450nm（近红外二区）区域的近红外量子点及其成像。此外，我们总结了生物成像的最新进展，并讨论了近红外量子点的未来趋势，包括II-VI族、IV-VI族、I-VI族、I-III-VI族、III-V族和IV族半导体。
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