Sailer Anna M, Schurink Geert Willem H, Wildberger Joachim E, de Graaf Rick, van Zwam Willem H, de Haan Michiel W, Kemerink Gerrit J, Jeukens Cécile R L P N
Department of Radiology, Maastricht University Medical Centre (MUMC), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands,
Cardiovasc Intervent Radiol. 2015 Feb;38(1):112-20. doi: 10.1007/s00270-014-0900-7. Epub 2014 May 6.
To evaluate patients radiation exposure of abdominal C-arm cone beam computed tomography (CBCT).
This prospective study was approved by the institutional review board; written, informed consent was waived. Radiation exposure of abdominal CBCT was evaluated in 40 patients who underwent CBCT during endovascular interventions. Dose area product (DAP) of CBCT was documented and effective dose (ED) was estimated based on organ doses using dedicated Monte Carlo simulation software with consideration of X-ray field location and patients' individual body weight and height. Weight-dependent ED per DAP conversion factors were calculated. CBCT radiation dose was compared to radiation dose of procedural fluoroscopy. CBCT dose-related risk for cancer was assessed.
Mean ED of abdominal CBCT was 4.3 mSv (95 % confidence interval [CI] 3.9; 4.8 mSv, range 1.1-7.4 mSv). ED was significantly higher in the upper than in the lower abdomen (p = 0.003) and increased with patients' weight (r = 0.55, slope = 0.045 mSv/kg, p < 0.001). Radiation exposure of CBCT corresponded to the radiation exposure of on average 7.2 fluoroscopy minutes (95 % CI 5.5; 8.8 min) in the same region of interest. Lifetime risk of exposure related cancer death was 0.033 % or less depending on age and weight.
Mean ED of abdominal CBCT was 4.3 mSv depending on X-ray field location and body weight.
评估腹部C形臂锥束计算机断层扫描（CBCT）患者的辐射暴露情况。
本前瞻性研究经机构审查委员会批准；书面知情同意书被豁免。对40例在血管内介入治疗期间接受CBCT检查的患者的腹部CBCT辐射暴露情况进行评估。记录CBCT的剂量面积乘积（DAP），并使用专用的蒙特卡罗模拟软件，在考虑X射线场位置以及患者个体体重和身高的情况下，根据器官剂量估算有效剂量（ED）。计算每DAP转换因子的体重依赖性ED。将CBCT辐射剂量与程序透视的辐射剂量进行比较。评估CBCT剂量相关的癌症风险。
腹部CBCT的平均ED为4.3 mSv（95%置信区间[CI] 3.9；4.8 mSv，范围1.1 - 7.4 mSv）。上腹部的ED显著高于下腹部（p = 0.003），且随患者体重增加而增加（r = 0.55，斜率 = 0.045 mSv/kg，p < 0.001）。CBCT的辐射暴露相当于在相同感兴趣区域平均7.2分钟透视的辐射暴露（95% CI 5.5；8.8分钟）。根据年龄和体重，暴露相关癌症死亡的终身风险为0.033%或更低。
根据X射线场位置和体重，腹部CBCT的平均ED为4.3 mSv。
