De Wilde Rudy Leon, Rafei Afsaneh, Herrmann Anja
Department of Gynecology, Obstetrics and Gynecological Oncology, Pius-Hospital, Carl von Ossietzky University, Oldenburg, Germany,
Arch Gynecol Obstet. 2014 Nov;290(5):973-8. doi: 10.1007/s00404-014-3265-x. Epub 2014 May 6.
Determination of early disease recurrence in patients with early-stage endometrial cancer operated laparoscopically without pelvic or paraaortic lymphadenectomy.
Retrospective chart review of all patients with endometrial carcinoma operated with laparoscopic-assisted vaginal hysterectomy with bilateral salpingo-oophorectomy between 2004 and 2008.
81 patients were eligible for data analysis. The operation time varied between 32 and 284 min. None of the patients suffered serious intraoperative complications. All patients had endometrial carcinoma of endometrioid type. As adjuvant therapy, patients received no further therapy (n = 30), radiation with brachytherapy with an afterloading technique alone (n = 36) or brachytherapy in combination with percutaneous radiation (n = 15). The observation period varied between 19 and 28 months (median 26 months). No patients were lost to follow-up. During the observation period, none of the patients had recurrence of disease or died.
Laparoscopic-assisted vaginal hysterectomy with bilateral salpingo-oophorectomy without pelvic or paraaortic lymphadenectomy combined with stage-adapted postoperative irradiation is a safe and efficient treatment option for patients with early-stage endometrial cancer of the endometriod type regarding early disease recurrence.
确定未行盆腔或腹主动脉旁淋巴结清扫术的腹腔镜手术早期子宫内膜癌患者疾病的早期复发情况。
回顾性分析2004年至2008年间所有接受腹腔镜辅助阴式子宫切除术加双侧输卵管卵巢切除术的子宫内膜癌患者的病历。
81例患者符合数据分析条件。手术时间在32至284分钟之间。无患者发生严重术中并发症。所有患者均为子宫内膜样型子宫内膜癌。作为辅助治疗，患者未接受进一步治疗（n = 30）、仅接受后装技术近距离放疗（n = 36）或近距离放疗联合经皮放疗（n = 15）。观察期在19至28个月之间（中位值26个月）。无患者失访。在观察期内，无患者疾病复发或死亡。
对于早期子宫内膜样型子宫内膜癌患者，未行盆腔或腹主动脉旁淋巴结清扫术的腹腔镜辅助阴式子宫切除术加双侧输卵管卵巢切除术联合根据分期调整的术后放疗是一种安全有效的治疗选择，可预防疾病早期复发。
