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一名婴儿出现反复喘息伴肺发育不全。

Pulmonary hypoplasia presenting with recurrent wheezing in an infant.

作者信息

Çeliksoy Mehmet Halil, Tander Burak, Aşılıoğlu Nazik, Barış Yakup Sancar, Yıldıran Alişan

机构信息

Pediatric Allergy and Immunology, Ondokuz Mayıs University Medical Faculty, Samsun, Turkey.

Pediatric Surgery, Ondokuz Mayıs University Medical Faculty, Samsun, Turkey.

出版信息

Clin Respir J. 2015 Oct;9(4):497-500. doi: 10.1111/crj.12158. Epub 2014 May 27.

Abstract

Pulmonary hypoplasia is characterized by decrease in the number and size of pulmonary airways, alveoli and vessels. In autopsy, pulmonary hypoplasia is a major cause of death in neonates and infants. The disease is usually diagnosed in childhood period. Although it mimics lung parenchymal disease and other vascular abnormalities radiologically, it is easily recognized with computed tomography angiography and magnetic resonance angiography examinations. In 50% of patients, concomitant cardiovascular, neuromuscular, gastrointestinal tract, and urogenital anomalies are also available. There are two types of pulmonary hypoplasia: primary and secondary. Primary unilateral pulmonary hypoplasia may be asymptomatic and the tendency for bronchopulmonary infections is often increased in children. In this case report, a 22-month-old male patient characterized by recurrent infections and recurrent wheezes in infantile period, whose episodes of wheezing regressed after the pulmonectomy, was presented.

摘要

肺发育不全的特征是肺气道、肺泡和血管的数量及大小减少。在尸检中,肺发育不全是新生儿和婴儿死亡的主要原因。该疾病通常在儿童期被诊断出来。尽管在放射学上它与肺实质疾病和其他血管异常相似,但通过计算机断层血管造影和磁共振血管造影检查很容易识别。50%的患者还伴有心血管、神经肌肉、胃肠道和泌尿生殖系统异常。肺发育不全有两种类型:原发性和继发性。原发性单侧肺发育不全可能无症状,儿童期支气管肺部感染的倾向通常会增加。在本病例报告中,介绍了一名22个月大的男性患者,其在婴儿期以反复感染和反复喘息为特征,肺切除术后喘息发作消退。

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