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成人眼睑黄色肉芽肿的不寻常表现。

Unusual presentation of xanthogranuloma on the eyelid of an adult.

作者信息

Chiang Elizabeth, Lissner Gary, Bryar Paul J

机构信息

Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, U.S.A.

出版信息

Ophthalmic Plast Reconstr Surg. 2014 Nov-Dec;30(6):e155-6. doi: 10.1097/01.iop.0000440703.67932.37.

DOI:10.1097/01.iop.0000440703.67932.37
PMID:24801255
Abstract

A 46-year-old man presented with an unusual papillary eyelid lesion in which histopathological study revealed a cutaneous xanthogranuloma. The clinical appearance was distinctively different from juvenile xanthogranuloma. There was no evidence of an infiltrative and orbital process consistent with adult orbital xanthogranulomatous disease. The histopathologic examination of the lesion revealed well-differentiated histiocytes with foamy cytoplasm. Immunohistochemistry stains were positive for CD163 and Factor XIIIa and negative for CD34, CD1A, CD117, and S100. The final histopathologic diagnosis was cutaneous xanthogranuloma.

摘要

一名46岁男性出现了一种不寻常的眼睑乳头状病变，组织病理学研究显示为皮肤黄色肉芽肿。其临床表现与幼年性黄色肉芽肿明显不同。没有证据表明存在与成人眼眶黄色肉芽肿性疾病一致的浸润性眼眶病变。病变的组织病理学检查显示有胞质呈泡沫状的分化良好的组织细胞。免疫组化染色CD163和因子ⅩⅢa呈阳性，而CD34、CD1A、CD117和S100呈阴性。最终组织病理学诊断为皮肤黄色肉芽肿。

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