Qiao Yanli, An Guoying, Chen Guoqing, Zheng Shanguang, Ni Liangchun, Wang Weixin, Ma Linfeng
Shandong Provincial Key Laboratory of Cardiac Disease Diagnosis and Treatment, Department of Cardiac Surgery, Jining Medical University Affiliated Hospital, Jining 272029, Shandong, China.
Shandong Provincial Key Laboratory of Cardiac Disease Diagnosis and Treatment, Department of Cardiac Surgery, Jining Medical University Affiliated Hospital, Jining 272029, Shandong, China.
Heart Lung Circ. 2014 Sep;23(9):847-51. doi: 10.1016/j.hlc.2014.03.009. Epub 2014 Mar 21.
This study aimed to investigate feasibility and safety of minimally invasive video-assisted surgery for double-valve (mitral and aortic) replacement through right anterolateral minithoracotomy.
Between February 2011 and April 2013, 60 patients with combined valvular disease underwent double valve replacement, 26 of them by minimally invasive video-assisted surgery through right anterolateral minithoracotomy (study group) and 34 by median sternotomy (control group). Peripheral cardiopulmonary bypass (CPB) was established through right femoral artery and vein. The incision was made around the right breast approximately 5 cm in length. Pericardiotomy, bicaval occlusion, atriotomy and aortotomy, and double valve replacement were performed with thoracoscope.
In the study group, times of CPB and aortic cross-clamp were 146.5 ± 40.5 min and 91.5 ± 23.4 min, respectively, which were significantly different from those in the control group, 115.4 ± 26.5 min and 75.4 ± 16.5 min (P<0.05). Thoracic drainage in the study group was significantly lower than the control group, 587 ± 245 ml (study group) versus 756 ± 267 ml (control group) (P<0.05). Length of ICU and postoperative hospital stay were shorter in the study group, 1.9 ± 0.8 and 8.7 ± 4.5 days versus 2.8 ± 1.3 and 11.2 ± 5.6 days in the control group (P<0.05), respectively. There was no statistical difference in the postoperative results of TTE (transthoracic echocardiography) (P>0.05). All patients recovered smoothly with follow-up of six months to two years, with no severe complications.
Minimally invasive video-assisted procedure through right anterolateral minithoracotomy is a new promising approach for double valve replacement. Our study suggested that this approach was feasible, safe and had cosmetic effects.
本研究旨在探讨经右前外侧小切口胸腔镜辅助下双瓣(二尖瓣和主动脉瓣)置换术的可行性和安全性。
2011年2月至2013年4月,60例心脏瓣膜病患者接受双瓣置换术,其中26例采用经右前外侧小切口胸腔镜辅助下微创外科手术(研究组),34例采用正中胸骨切开术(对照组)。通过右股动静脉建立外周体外循环(CPB)。在右乳房周围做一个约5cm长的切口。在胸腔镜下进行心包切开、双腔静脉阻断、心房切开和主动脉切开以及双瓣置换。
研究组CPB时间和主动脉阻断时间分别为146.5±40.5分钟和91.5±23.4分钟,与对照组的115.4±26.5分钟和75.4±16.5分钟相比有显著差异(P<0.05)。研究组胸腔引流量明显低于对照组,分别为587±245ml(研究组)和756±267ml(对照组)(P<0.05)。研究组重症监护病房(ICU)住院时间和术后住院时间较短,分别为1.9±0.8天和8.7±4.5天,而对照组分别为2.8±1.3天和11.2±5.6天(P<0.05)。经胸超声心动图(TTE)术后结果无统计学差异(P>0.05)。所有患者均顺利康复,随访6个月至2年,无严重并发症。
经右前外侧小切口胸腔镜辅助下的微创技术是一种有前景的双瓣置换新方法。我们的研究表明该方法可行、安全且具有美容效果。