Zhang Shuqi, Holmes Matthew, Li Li
1Louisiana State University, Baton Rouge, LA, USA.
Int J Neurosci. 2015 Mar;125(3):201-7. doi: 10.3109/00207454.2014.920332. Epub 2014 Jun 4.
Examining degenerative sensory and reflexive activity among people with peripheral neuropathy (PN) is important for clinical examinations and understanding relevant neural impairments. However, other than the test of presynaptic inhibition, the reliability of other related tests is largely unknown. The purpose of this project was to examine the test-retest reliability of lower extremity sensory and reflexive measures in people with PN. Twelve participants (8 women, 4 men, age = 72.5 ± 9.2 years) diagnosed with PN were assessed on two occasions at least 7 d apart. Plantar sensitivity, H-reflex and active and passive ankle proprioception (AAP and PAP) were tested. Paired student's t-test and Intraclass correlation coefficients (ICC) were used for statistical analysis. Significant difference was observed in AAP at 0º position (p = 0.04). No other significant differences were observed. Moderate to high reliability was observed at measures of Plantar sensitivity (0.92), peak to peak H (0.71) and M (0.84) waves, latency between H and M (0.78), H-Index (0.85), AAP (0.62) and PAP index (0.60). Low reliability was observed of other parameters. The measures of Hmax, Mmax, latency, H-Index, plantar sensitivity and AAP & PAP indices of proprioception tests can be measured reliably for further study in this population.
研究周围神经病变（PN）患者的退行性感觉和反射活动对于临床检查以及理解相关神经损伤具有重要意义。然而，除了突触前抑制测试外，其他相关测试的可靠性在很大程度上尚不清楚。本项目的目的是检验PN患者下肢感觉和反射测量的重测可靠性。对12名被诊断为PN的参与者（8名女性，4名男性，年龄 = 72.5 ± 9.2岁）进行了两次评估，间隔至少7天。测试了足底敏感性、H反射以及主动和被动踝关节本体感觉（AAP和PAP）。采用配对学生t检验和组内相关系数（ICC）进行统计分析。在0º位置的AAP中观察到显著差异（p = 0.04）。未观察到其他显著差异。在足底敏感性（0.92）、峰峰值H（0.71）和M（0.84）波、H与M之间的潜伏期（0.78）、H指数（0.85）、AAP（0.62）和PAP指数（0.60）的测量中观察到中度至高可靠性。其他参数的可靠性较低。本体感觉测试的Hmax、Mmax、潜伏期、H指数、足底敏感性以及AAP和PAP指数的测量可以可靠地进行，以便在该人群中进行进一步研究。
