Department of Medicine, College of Medicine, King Saud University, P.O. Box 2925 (38), Riyadh 11461, Saudi Arabia.
Clinical Chemistry Unit, Department of Pathology, College of Medicine, King Saud University, P.O. Box 2925 (30), Riyadh 11461, Saudi Arabia ; Department of Medical Biochemistry, Faculty of Medicine, Ain Shams University, Abbassia, Cairo 11566, Egypt.
Int J Endocrinol. 2014;2014:794943. doi: 10.1155/2014/794943. Epub 2014 Apr 3.
Few studies have been reported from the Kingdom of Saudi Arabia (SA) to describe the clinical presentation and long term outcomes of subacute thyroiditis (SAT). Our aim was to review the demographic, anthropometric, clinical presentation, laboratory results, treatment, and disease outcome in Riyadh region and to compare those with results from different regions of the Kingdom and different parts of the world. We reviewed the medical files of patients who underwent thyroid uptake scan during an 8-year period in King Khalid University Hospital. Only 25 patients had confirmed diagnosis of thyroiditis. Age and gender distribution were similar to other studies. Most patients presented with palpitation, goiter, and weight change. Elevated thyroid hormones, suppressed thyroid-stimulating hormone, and elevated ESR were reported. Among those, 7 cases of SAT were recorded. β -Blockers were prescribed to 57% and nonsteroidal anti-inflammatory drugs to 29% of SAT. Long follow-up demonstrated that 85.7% of SAT cases recovered, while 14.3% developed permanent hypothyroidism. In conclusion, SAT is uncommon in the central region of SA. Compared to the western region, corticosteroid is not commonly prescribed, and permanent hypothyroidism is not uncommon. A nation-wide epidemiological study to explain these interprovincial differences is warranted.
沙特阿拉伯(SA)的少数研究报告描述了亚急性甲状腺炎(SAT)的临床表现和长期结局。我们的目的是回顾利雅得地区的人口统计学、人体测量学、临床表现、实验室结果、治疗和疾病结局,并将其与王国其他地区和世界其他地区的结果进行比较。我们回顾了在 King Khalid University Hospital 进行甲状腺摄取扫描的 8 年期间的患者的医疗档案。只有 25 名患者被确诊为甲状腺炎。年龄和性别分布与其他研究相似。大多数患者表现为心悸、甲状腺肿和体重变化。报告了甲状腺激素升高、促甲状腺激素抑制和 ESR 升高。其中,记录了 7 例 SAT。β受体阻滞剂被开给 57%的 SAT 患者,非甾体抗炎药被开给 29%的 SAT 患者。长期随访显示,85.7%的 SAT 病例痊愈,而 14.3%的患者发展为永久性甲状腺功能减退。总之,SAT 在 SA 的中心地区并不常见。与西部地区相比,皮质类固醇并不常用,永久性甲状腺功能减退也不罕见。有必要进行全国性的流行病学研究来解释这些省级之间的差异。