Liu Huifang, Liu Ying, Yang Lin, Wang Chunyan, Wu Yuanchao, He Chengqi
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2014 Feb;31(1):48-52.
We investigated the effects and optimal treatment frequency of pulsed electromagnetic fields (PEMFs) on postmenopausal osteoporosis (PMO). A comparison was performed with the cyclical alendronate and a course of PEMFs in the treatment for postmenopausal osteoporosis on bone mineral density (BMD), pain intensity and balance function. There was no significant difference between the two groups on mean percentage changes from baseline of BMD within 24 weeks after random treatments (P > or = 0.05). However, at the ends of 48 weeks and 72 weeks, the BMD of the PEMFs group were significantly lower than that of the alendronate group (P < 0.05). No significant difference was detected between the two groups with regard to treatment effects on Visual Analogue Scale score, the Timed Up & Go Test and Berg Balance Scale score. Compared with cyclical alendronate, a course of PEMFs was as effective as alendronate in treating PMO for at least 24 weeks. So its optimal treatment frequency for PMO may be one course per six months.
我们研究了脉冲电磁场(PEMFs)对绝经后骨质疏松症(PMO)的影响及最佳治疗频率。将其与周期性阿仑膦酸盐以及一个疗程的PEMFs在治疗绝经后骨质疏松症时对骨密度(BMD)、疼痛强度和平衡功能的影响进行了比较。随机治疗后24周内,两组BMD自基线的平均百分比变化无显著差异(P≥0.05)。然而,在48周和72周结束时,PEMFs组的BMD显著低于阿仑膦酸盐组(P<0.05)。两组在视觉模拟评分、计时起立行走测试和伯格平衡量表评分的治疗效果方面未检测到显著差异。与周期性阿仑膦酸盐相比,一个疗程的PEMFs在治疗PMO至少24周时与阿仑膦酸盐效果相当。因此,其治疗PMO的最佳频率可能为每六个月一个疗程。