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胆脂瘤手术中面神经管裂开的术中发生率:一项前瞻性病例对照研究及文献综述。

The intra-operative incidence of Fallopian canal dehiscence during surgery for cholesteatoma: a prospective case-control study and review of the literature.

作者信息

Trinidade A, Yung M W

机构信息

Department of ENT, Ipswich General Hospital, Ipswich, UK.

出版信息

Clin Otolaryngol. 2014 Jun;39(3):138-44. doi: 10.1111/coa.12256.

Abstract

OBJECTIVE

To investigate Fallopian canal dehiscence (FCD) during cholesteatoma surgery.

STUDY DESIGN

Prospective case-control study.

PATIENTS

Four hundred and one patients with cholesteatoma and 172 with otosclerosis.

INTERVENTIONS

Therapeutic.

SETTING

District general hospital.

MAIN OUTCOME MEASURES

(i) Intra-operative incidence of FCD during (a) surgery for cholesteatoma versus a homogeneous control group (patients with otosclerosis); (b) revision surgery for cholesteatoma as compared to primary surgery. (ii) Intra-operative incidence of a fistula if FCD is present.

RESULTS

Data were prospectively collected and analysed using chi-square tests. FCD was found in 19% of cases versus 5.2% of controls. Intra-operative incidence of (i) FCD during cholesteatoma surgery versus otosclerosis surgery was statistically very highly significant (P < 0.0001, OR = 5.43); (ii) FCD during revision versus primary cholesteatoma surgery was not statistically significant (P = 0.83); and (iii) encountering a fistula in the presence of FCD during cholesteatoma surgery was statistically very highly significant (P < 0.0001, OR = 6.71).

CONCLUSIONS

A surgeon is more likely to encounter FCD during cholesteatoma surgery than in stapes surgery. If during cholesteatoma surgery FCD is found, then a fistula is also more likely to be present, mainly of the semicircular canal. The incidence of FCD is not increased in revision surgery. These findings are very relevant for any otologist undertaking cholesteatoma surgery.

摘要

目的

研究胆脂瘤手术中面神经管裂(FCD)情况。

研究设计

前瞻性病例对照研究。

患者

401例胆脂瘤患者和172例耳硬化症患者。

干预措施

治疗性。

研究地点

地区综合医院。

主要观察指标

(i)在(a)胆脂瘤手术与同质对照组(耳硬化症患者)手术期间;(b)胆脂瘤翻修手术与初次手术期间,FCD的术中发生率。(ii)若存在FCD,术中出现瘘管的发生率。

结果

前瞻性收集数据并使用卡方检验进行分析。FCD在19%的病例中被发现,而对照组为5.2%。(i)胆脂瘤手术与耳硬化症手术期间FCD的术中发生率在统计学上差异极显著(P < 0.0001,OR = 5.43);(ii)胆脂瘤翻修手术与初次手术期间FCD的术中发生率无统计学差异(P = 0.83);(iii)胆脂瘤手术中在存在FCD的情况下遇到瘘管在统计学上差异极显著(P < 0.0001,OR = 6.71)。

结论

与镫骨手术相比,外科医生在胆脂瘤手术中更有可能遇到FCD。如果在胆脂瘤手术中发现FCD,那么也更有可能存在瘘管,主要是半规管瘘管。FCD的发生率在翻修手术中并未增加。这些发现对于任何进行胆脂瘤手术的耳科医生都非常重要。

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