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面神经管-外侧半规管裂的特征:未被充分认识的第三窗

Characteristics of the Facial Canal-Lateral Canal Dehiscence: The Under-recognized Third Window.

作者信息

Garvis William J, Johnson Blake A, Kluesner Katherine E, Garvis Stephanie M

机构信息

Ear, Nose & Throat Specialty Care of Minnesota Minneapolis Minnesota USA.

Neuroradiology Section Rayus Radiology Minneapolis Minnesota USA.

出版信息

OTO Open. 2025 Feb 17;9(1):e70085. doi: 10.1002/oto2.70085. eCollection 2025 Jan-Mar.

DOI:10.1002/oto2.70085
PMID:39963505
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11831756/
Abstract

OBJECTIVE

We aimed to establish normative data on the bony partition between the facial canal (FC) and the lateral semicircular canal (LSCC) and present our initial series of cases in which an FC-LSCC dehiscence was identified based on these anatomic criteria, with or without other third window pathologies.

STUDY DESIGN

Normative data: Analysis of archival otopathological human temporal bone specimens and computed tomography (CT) scans. Clinical data: Case studies.

SETTING

An otopathology laboratory and a specialized otolaryngology, head and neck surgery outpatient clinic.

METHODS

We measured the bony partition thickness between the FC-LSCC in human temporal bone otopathological specimens and CT scans. The clinical study involved a series of reviews of patients with FC-LSCC, presenting clinical data and CT images.

RESULTS

The average thickness of the bony partition measured via CT was 0.6 mm ± 0.2 mm, whereas in otopathological specimens it was 0.56 mm ± 0.17 mm. We identified 34 patients with FC-LSCC dehiscence. The most frequently reported symptoms were hearing loss (44%), dizziness/vertigo (44%), and tinnitus (41%). Of the patients, 15 (44%) had more than 1 site of bone dehiscence and 21 (62%) had bilateral FC-LSCC dehiscence. We then identified 36 patients in whom only FC-LSCC dehiscences were found and provided characteristics for this population.

CONCLUSION

Our study provides normative characteristics on the bony partition between the FC-LSCC and the signs and symptoms of this third window abnormality. FC-LSCC should be included in differential diagnoses of patients presenting with third window syndrome symptoms.

摘要

目的

我们旨在建立面神经管(FC)与外侧半规管(LSCC)之间骨分隔的规范数据,并展示我们根据这些解剖学标准首次发现的FC-LSCC裂开系列病例,无论是否伴有其他第三窗病变。

研究设计

规范数据:对存档的人类颞骨耳病理标本和计算机断层扫描(CT)进行分析。临床数据:病例研究。

研究地点

耳病理实验室和专门的耳鼻喉头颈外科门诊。

方法

我们测量了人类颞骨耳病理标本和CT扫描中FC-LSCC之间的骨分隔厚度。临床研究涉及对FC-LSCC患者的一系列回顾,展示临床数据和CT图像。

结果

通过CT测量的骨分隔平均厚度为0.6毫米±0.2毫米,而在耳病理标本中为0.56毫米±0.17毫米。我们确定了34例FC-LSCC裂开患者。最常报告的症状是听力损失(44%)、头晕/眩晕(44%)和耳鸣(41%)。其中15例(44%)有不止一处骨裂开,21例(62%)有双侧FC-LSCC裂开。然后我们确定了36例仅发现FC-LSCC裂开的患者,并给出了该人群的特征。

结论

我们的研究提供了FC-LSCC之间骨分隔的规范特征以及这种第三窗异常的体征和症状。FC-LSCC应纳入出现第三窗综合征症状患者的鉴别诊断中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec3b/11831756/4b95a203ee2d/OTO2-9-e70085-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec3b/11831756/ad3f8def5238/OTO2-9-e70085-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec3b/11831756/2f9de1a509d6/OTO2-9-e70085-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec3b/11831756/4b95a203ee2d/OTO2-9-e70085-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec3b/11831756/ad3f8def5238/OTO2-9-e70085-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec3b/11831756/2f9de1a509d6/OTO2-9-e70085-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec3b/11831756/4b95a203ee2d/OTO2-9-e70085-g002.jpg

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本文引用的文献

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2
Gray-Scale Inversion on High Resolution Computed Tomography of the Temporal Bone: An Observational Study.高分辨率 CT 颞骨灰度反转:一项观察性研究。
Ann Otol Rhinol Laryngol. 2021 Oct;130(10):1125-1131. doi: 10.1177/0003489421996844. Epub 2021 Feb 25.
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Microcrack surface density in the human otic capsule: An unbiased stereological quantification.
人内耳囊微裂纹表面密度:一种无偏体视学定量分析。
Anat Rec (Hoboken). 2021 May;304(5):961-967. doi: 10.1002/ar.24535. Epub 2020 Oct 19.
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Prevalence of facial canal dehiscence and other bone defects by computed tomography.基于 CT 的面神经管裂及其他骨缺损的患病率。
Eur Arch Otorhinolaryngol. 2020 Oct;277(10):2681-2686. doi: 10.1007/s00405-020-06013-8. Epub 2020 May 7.
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Prevalence of Radiographic Cochlear-Facial Nerve Dehiscence.影像学耳蜗面神经裂的发生率。
Otol Neurotol. 2018 Dec;39(10):1319-1325. doi: 10.1097/MAO.0000000000002015.
6
Cochlear-Internal Canal and Cochlear-Facial Dehiscence: A Novel Entity.耳蜗-内耳道及耳蜗-面神经裂缺:一种新发现的情况。
J Int Adv Otol. 2018 Aug;14(2):334-336. doi: 10.5152/iao.2018.5089.
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Inner ear ossification and mineralization kinetics in human embryonic development - microtomographic and histomorphological study.内耳骨化和矿化动力学的人类胚胎发育 - 显微断层和组织形态学研究。
Sci Rep. 2017 Jul 6;7(1):4825. doi: 10.1038/s41598-017-05151-0.
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Superior Canal Dehiscence Syndrome: Lessons from the First 20 Years.半规管裂综合征:前20年的经验教训
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J Neurol Surg B Skull Base. 2015 Dec;76(6):421-5. doi: 10.1055/s-0035-1551667. Epub 2015 May 29.