Unlu Ezgi, Akay Bengu N, Erdem Cengizhan
Department of Dermatology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey.
J Dermatol. 2014 Jul;41(7):598-603. doi: 10.1111/1346-8138.12491. Epub 2014 May 8.
Dermatoscopic analysis of melanocytic lesions using the CASH algorithm has rarely been described in the literature. The purpose of this study was to compare the sensitivity, specificity, and diagnostic accuracy rates of the ABCD rule of dermatoscopy, the seven-point checklist, the three-point checklist, and the CASH algorithm in the diagnosis and dermatoscopic evaluation of melanocytic lesions on the hairy skin. One hundred and fifteen melanocytic lesions of 115 patients were examined retrospectively using dermatoscopic images and compared with the histopathologic diagnosis. Four dermatoscopic algorithms were carried out for all lesions. The ABCD rule of dermatoscopy showed sensitivity of 91.6%, specificity of 60.4%, and diagnostic accuracy of 66.9%. The seven-point checklist showed sensitivity, specificity, and diagnostic accuracy of 87.5, 65.9, and 70.4%, respectively; the three-point checklist 79.1, 62.6, 66%; and the CASH algorithm 91.6, 64.8, and 70.4%, respectively. To our knowledge, this is the first study that compares the sensitivity, specificity and diagnostic accuracy of the ABCD rule of dermatoscopy, the three-point checklist, the seven-point checklist, and the CASH algorithm for the diagnosis of melanocytic lesions on the hairy skin. In our study, the ABCD rule of dermatoscopy and the CASH algorithm showed the highest sensitivity for the diagnosis of melanoma.
利用CASH算法对黑素细胞性皮损进行皮肤镜分析在文献中鲜有描述。本研究的目的是比较皮肤镜ABCD规则、七点检查表、三点检查表和CASH算法在毛发皮肤黑素细胞性皮损诊断及皮肤镜评估中的敏感性、特异性和诊断准确率。回顾性分析115例患者的115个黑素细胞性皮损的皮肤镜图像，并与组织病理学诊断结果进行比较。对所有皮损均采用四种皮肤镜算法。皮肤镜ABCD规则的敏感性为91.6%，特异性为60.4%，诊断准确率为66.9%。七点检查表的敏感性、特异性和诊断准确率分别为87.5%、65.9%和70.4%；三点检查表分别为79.1%、62.6%、66%；CASH算法分别为91.6%、64.8%和70.4%。据我们所知，这是第一项比较皮肤镜ABCD规则、三点检查表、七点检查表和CASH算法在毛发皮肤黑素细胞性皮损诊断中的敏感性、特异性和诊断准确率的研究。在我们的研究中，皮肤镜ABCD规则和CASH算法在黑色素瘤诊断中显示出最高的敏感性。
