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Efficient tissue-specific expression of bovine alpha-lactalbumin in transgenic mice.

作者信息

Vilotte J L, Soulier S, Stinnakre M G, Massoud M, Mercier J C

机构信息

Laboratoire de Génétique Biochimique, Institut National de la Recherche Agronomique, Jouy-en-Josas, France.

出版信息

Eur J Biochem. 1989 Dec 8;186(1-2):43-8. doi: 10.1111/j.1432-1033.1989.tb15175.x.

DOI:10.1111/j.1432-1033.1989.tb15175.x
PMID:2480895
Abstract

Transgenic mice carrying a 3.2-kb genomic fragment comprising the bovine alpha-lactalbumin gene transcription unit with 750 bp and 336 bp of 5' and 3' flanking regions, respectively, were generated. Tissue-specific expression of the transgene was observed in five out of the six lines analyzed at levels close to the endogenous gene in two of them.

摘要

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