McIntyre A S, Morris D L, Sloan R L, Robertson C S, Harrison J, Burnham W R, Atkinson M
Oldchurch Hospital, Romford, Essex, United Kingdom.
Gastrointest Endosc. 1989 Nov-Dec;35(6):531-5. doi: 10.1016/s0016-5107(89)72905-9.
Patients with malignant esophageal stricture and dysphagia were prospectively randomized to receive palliative therapy with the bipolar tumor probe (17) or prosthetic tube insertion (13). Both treatments gave good relief of dysphagia compared with pretreatment values on a dysphagia score, the results being statistically significant (p less than 0.005). However, there was no difference in the improvement achieved by one method compared with the other. The tumor probe was not difficult to use and complication rates were comparable. In the Atkinson tube group, two patients developed complications related to the position of the prosthesis and in three others food blocked the tube. Treatment with the tumor probe needed repeating at intervals (median, 28 days; range, 2 to 86 days) in all but four individuals to maintain palliation, with each patient needing a median of two treatments (range, 1 to 8). The probe may have advantages in very high esophageal lesions and may facilitate the treatment of tumor overgrowth or undergrowth of a tube. The prosthetic tube may give long-lasting relief of dysphagia and remains the treatment of choice for bronchopulmonary fistulas.
患有恶性食管狭窄和吞咽困难的患者被前瞻性随机分组，分别接受双极肿瘤探头姑息治疗（17例）或置入假体管（13例）。与吞咽困难评分的预处理值相比，两种治疗方法均能显著缓解吞咽困难，结果具有统计学意义（p<0.005）。然而，两种方法在改善程度上没有差异。肿瘤探头使用并不困难，并发症发生率相当。在阿特金森管组中，有2例患者出现与假体位置相关的并发症，另有3例患者食物堵塞了管子。除4例患者外，所有患者均需定期（中位时间28天；范围2至86天）重复使用肿瘤探头治疗以维持姑息治疗效果，每位患者中位需要接受2次治疗（范围1至8次）。该探头在治疗极高位置的食管病变时可能具有优势，并且可能有助于处理肿瘤过度生长或管子生长不足的情况。假体管可能会长期缓解吞咽困难，仍是支气管肺瘘的首选治疗方法。
