Okuchi Sachi, Okada Tomohisa, Fujimoto Koji, Fushimi Yasutaka, Kido Aki, Yamamoto Akira, Kanagaki Mitsunori, Dodo Toshiki, Mehemed Taha M, Miyazaki Mitsue, Zhou Xiangzhi, Togashi Kaori
Department of Diagnostic Radiology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawaharacho, Sakyo-ku, Kyoto 606-8507, Japan.
Department of Diagnostic Radiology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawaharacho, Sakyo-ku, Kyoto 606-8507, Japan.
Acad Radiol. 2014 Jun;21(6):812-6. doi: 10.1016/j.acra.2014.03.007.
To optimize visualization of lenticulostriate artery (LSA) by time-of-flight (TOF) magnetic resonance angiography (MRA) with slice-selective off-resonance sinc (SORS) saturation transfer contrast pulses and to compare capability of optimal TOF-MRA and flow-sensitive black-blood (FSBB) MRA to visualize the LSA at 3T.
This study was approved by the local ethics committee, and written informed consent was obtained from all the subjects. TOF-MRA was optimized in 20 subjects by comparing SORS pulses of different flip angles: 0, 400°, and 750°. Numbers of LSAs were counted. The optimal TOF-MRA was compared to FSBB-MRA in 21 subjects. Images were evaluated by the numbers and length of visualized LSAs.
LSAs were significantly more visualized in TOF-MRA with SORS pulses of 400° than others (P < .003). When the optimal TOF-MRA was compared to FSBB-MRA, the visualization of LSA using FSBB (mean branch numbers 11.1, 95% confidence interval (CI) 10.0-12.1; mean total length 236 mm, 95% CI 210-263 mm) was significantly better than using TOF (4.7, 95% CI 4.1-5.3; 78 mm, 95% CI 67-89 mm) for both numbers and length of the LSA (P < .0001).
LSA visualization was best with 400° SORS pulses for TOF-MRA but FSBB-MRA was better than TOF-MRA, which indicates its clinical potential to investigate the LSA on a 3T magnetic resonance imaging.
通过使用具有切片选择性失谐 sinc（SORS）饱和转移对比脉冲的飞行时间（TOF）磁共振血管造影（MRA）优化豆纹动脉（LSA）的可视化，并比较优化后的 TOF-MRA 和血流敏感黑血（FSBB）MRA 在 3T 时可视化 LSA 的能力。
本研究经当地伦理委员会批准，并获得所有受试者的书面知情同意。通过比较不同翻转角（0°、400°和 750°）的 SORS 脉冲，对 20 名受试者的 TOF-MRA 进行优化。计算 LSA 的数量。在 21 名受试者中，将优化后的 TOF-MRA 与 FSBB-MRA 进行比较。通过可视化 LSA 的数量和长度对图像进行评估。
与其他翻转角相比，使用 400°SORS 脉冲的 TOF-MRA 能更显著地显示 LSA（P <.003）。当将优化后的 TOF-MRA 与 FSBB-MRA 进行比较时，就 LSA 的数量和长度而言，使用 FSBB 可视化 LSA（平均分支数 11.1，95%置信区间（CI）10.0 - 12.1；平均总长度 236 mm，95%CI 210 - 263 mm）明显优于使用 TOF（4.7，95%CI 4.1 - 5.3；78 mm，95%CI 67 - 89 mm）（P <.0001）。
对于 TOF-MRA，400°SORS 脉冲能实现最佳的 LSA 可视化，但 FSBB-MRA 优于 TOF-MRA，这表明其在 3T 磁共振成像上研究 LSA 的临床潜力。
