Basaran Ahmet, Basaran Mustafa, Basaran Betul, Sen Cihat, Martin James N
J Perinat Med. 2015 Jan;43(1):61-6. doi: 10.1515/jpm-2014-0109.
Considerable controversy continues to surround the management of severe preeclampsia and HELLP syndrome. Experts, researchers, and those published in the field were surveyed about their specific practices.
An extensive literature search was undertaken to identify the cohort of authors with recent publications on the subjects of preeclampsia (2009-2012) and HELLP syndrome (2005-2012). Online surveys were sent to all authors using the email addresses found in their publications.
Surveys were delivered by email to 363 authors of preeclampsia publications and 91 authors of HELLP syndrome publications. Completed surveys were received from 61 (13.4%) of the group. Except for consensus about the indication of corticosteroids for the enhancement of fetal lung maturation, there was considerable variation in corticosteroid practice and anesthesia techniques.
A marked diversity in practice characterized the clinical care rendered by experts in the field of preeclampsia and HELLP syndrome. Thus, there is an urgent need for well-designed and executed prospective clinical trials to improve the evidence for best consensus practice in this area of obstetrical medicine.
重度子痫前期和HELLP综合征的管理仍存在相当大的争议。我们对该领域的专家、研究人员及已发表相关文献者的具体实践进行了调查。
进行了广泛的文献检索，以确定近期发表过关于子痫前期（2009 - 2012年）和HELLP综合征（2005 - 2012年）相关主题文章的作者群体。通过在其发表文章中找到的电子邮箱地址向所有作者发送在线调查问卷。
通过电子邮件向363名子痫前期相关文章的作者和91名HELLP综合征相关文章的作者发送了调查问卷。该群体中有61人（13.4%）回复了完整的调查问卷。除了在使用糖皮质激素促进胎儿肺成熟的指征方面达成共识外，糖皮质激素的使用方法和麻醉技术存在相当大的差异。
子痫前期和HELLP综合征领域专家的临床实践存在显著差异。因此，迫切需要设计良好且执行严格的前瞻性临床试验，以完善该产科医学领域最佳共识实践的证据。
