McDonald Steve, Page Matthew J, Beringer Katherine, Wasiak Jason, Sprowson Andrew
School of Public Health & Preventive Medicine, Monash University, The Alfred Centre, 99 Commercial Road, Melbourne, Victoria, Australia, 3004.
Cochrane Database Syst Rev. 2014 May 13;2014(5):CD003526. doi: 10.1002/14651858.CD003526.pub3.
Hip or knee replacement is a major surgical procedure that can be physically and psychologically stressful for patients. It is hypothesised that education before surgery reduces anxiety and enhances clinically important postoperative outcomes.
To determine whether preoperative education in people undergoing total hip replacement or total knee replacement improves postoperative outcomes with respect to pain, function, health-related quality of life, anxiety, length of hospital stay and the incidence of adverse events (e.g. deep vein thrombosis).
We searched the Cochrane Central Register of Controlled Trials (2013, Issue 5), MEDLINE (1966 to May 2013), EMBASE (1980 to May 2013), CINAHL (1982 to May 2013), PsycINFO (1872 to May 2013) and PEDro to July 2010. We handsearched the Australian Journal of Physiotherapy (1954 to 2009) and reviewed the reference lists of included trials and other relevant reviews.
Randomised or quasi-randomised trials of preoperative education (verbal, written or audiovisual) delivered by a health professional within six weeks of surgery to people undergoing hip or knee replacement compared with usual care.
Two review authors independently assessed trial quality and extracted data. We analysed dichotomous outcomes using risk ratios. We combined continuous outcomes using mean differences (MD) or standardised mean differences (SMD) with 95% confidence intervals (CI). Where possible, we pooled data using a random-effects meta-analysis.
We included 18 trials (1463 participants) in the review. Thirteen trials involved people undergoing hip replacement, three involved people undergoing knee replacement and two included both people with hip and knee replacements. Only six trials reported using an adequate method of allocation concealment, and only two trials blinded participants. Few trials reported sufficient data to analyse the major outcomes of the review (pain, function, health-related quality of life, global assessment, postoperative anxiety, total adverse events and re-operation rate). There did not appear to be an effect of time on any outcome, so we chose to include only the latest time point available per outcome in the review.In people undergoing hip replacement, preoperative education may not offer additional benefits over usual care. The mean postoperative anxiety score at six weeks with usual care was 32.16 on a 60-point scale (lower score represents less anxiety) and was 2.28 points lower with preoperative education (95% confidence interval (CI) -5.68 to 1.12; 3 RCTs, 264 participants, low-quality evidence), an absolute risk difference of -4% (95% CI -10% to 2%). The mean pain score up to three months postoperatively with usual care was 3.1 on a 10-point scale (lower score represents less pain) and was 0.34 points lower with preoperative education (95% CI -0.94 to 0.26; 3 RCTs, 227 participants; low-quality evidence), an absolute risk difference of -3% (95% CI -9% to 3%). The mean function score at 3 to 24 months postoperatively with usual care was 18.4 on a 68-point scale (lower score represents better function) and was 4.84 points lower with preoperative education (95% CI -10.23 to 0.66; 4 RCTs, 177 participants; low-quality evidence), an absolute risk difference of -7% (95% CI -15% to 1%). The number of people reporting adverse events, such as infection and deep vein thrombosis, did not differ between groups, but the effect estimates are uncertain due to very low quality evidence (23% (17/75) reported events with usual care versus 18% (14/75) with preoperative education; risk ratio (RR) 0.79; 95% CI 0.19 to 3.21; 2 RCTs, 150 participants). Health-related quality of life, global assessment of treatment success and re-operation rates were not reported.In people undergoing knee replacement, preoperative education may not offer additional benefits over usual care. The mean pain score at 12 months postoperatively with usual care was 80 on a 100-point scale (lower score represents less pain) and was 2 points lower with preoperative education (95% CI -3.45 to 7.45; 1 RCT, 109 participants), an absolute risk difference of -2% (95% CI -4% to 8%). The mean function score at 12 months postoperatively with usual care was 77 on a 100-point scale (lower score represents better function) and was no different with preoperative education (0; 95% CI -5.63 to 5.63; 1 RCT, 109 participants), an absolute risk difference of 0% (95% CI -6% to 6%). The mean health-related quality of life score at 12 months postoperatively with usual care was 41 on a 100-point scale (lower score represents worse quality of life) and was 3 points lower with preoperative education (95% CI -6.38 to 0.38; 1 RCT, 109 participants), an absolute risk difference of -3% (95% CI -6% to 1%). The number of people reporting adverse events, such as infection and deep vein thrombosis, did not differ between groups (18% (11/60) reported events with usual care versus 13% (7/55) with preoperative education; RR 0.69; 95% CI 0.29 to 1.66; 1 RCT, 115 participants), an absolute risk difference of -6% (-19% to 8%). Global assessment of treatment success, postoperative anxiety and re-operation rates were not reported.
AUTHORS' CONCLUSIONS: Although preoperative education is embedded in the consent process, we are unsure if it offers benefits over usual care in terms of reducing anxiety, or in surgical outcomes, such as pain, function and adverse events. Preoperative education may represent a useful adjunct, with low risk of undesirable effects, particularly in certain patients, for example people with depression, anxiety or unrealistic expectations, who may respond well to preoperative education that is stratified according to their physical, psychological and social need.
髋关节或膝关节置换是一项重大外科手术,对患者而言可能在身体和心理上造成压力。据推测,术前教育可减轻焦虑并改善具有临床重要意义的术后结局。
确定全髋关节置换或全膝关节置换患者的术前教育在疼痛、功能、健康相关生活质量、焦虑、住院时间及不良事件(如深静脉血栓形成)发生率方面是否能改善术后结局。
我们检索了Cochrane对照试验中心注册库(2013年第5期)、MEDLINE(1966年至2013年5月)、EMBASE(1980年至2013年5月)、CINAHL(1982年至2013年5月)、PsycINFO(1872年至2013年5月)以及截至2010年7月的PEDro。我们手工检索了《澳大利亚物理治疗杂志》(1954年至2009年),并查阅了纳入试验及其他相关综述的参考文献列表。
由健康专业人员在手术六周内对髋关节或膝关节置换患者进行的术前教育(口头、书面或视听)的随机或半随机试验,与常规护理进行比较。
两位综述作者独立评估试验质量并提取数据。我们使用风险比分析二分结局。我们使用均值差(MD)或标准化均值差(SMD)及95%置信区间(CI)合并连续结局。在可能的情况下,我们使用随机效应荟萃分析汇总数据。
我们在综述中纳入了18项试验(1463名参与者)。13项试验涉及髋关节置换患者,3项试验涉及膝关节置换患者,2项试验同时纳入了髋关节和膝关节置换患者。只有6项试验报告使用了充分的分配隐藏方法,只有2项试验对参与者进行了盲法处理。很少有试验报告足够的数据来分析综述的主要结局(疼痛、功能、健康相关生活质量、总体评估、术后焦虑、总不良事件和再次手术率)。时间似乎对任何结局均无影响,因此我们选择在综述中仅纳入每个结局可获得的最新时间点的数据。在髋关节置换患者中,术前教育可能不会比常规护理带来更多益处。常规护理下六周时的术后平均焦虑评分为60分制中的32.16分(分数越低表示焦虑越少),术前教育使其降低2.28分(95%置信区间(CI)-5.68至1.12;3项随机对照试验,264名参与者,低质量证据),绝对风险差为-4%(95%CI -10%至2%)。常规护理下术后三个月内的平均疼痛评分为10分制中的3.1分(分数越低表示疼痛越少),术前教育使其降低0.34分(95%CI -0.94至0.26;3项随机对照试验,227名参与者;低质量证据),绝对风险差为-3%(95%CI -9%至3%)。常规护理下术后3至24个月的平均功能评分为68分制中的18.4分(分数越低表示功能越好),术前教育使其降低4.84分(95%CI -10.23至0.66;4项随机对照试验,177名参与者;低质量证据),绝对风险差为-7%(95%CI -15%至1%)。报告感染和深静脉血栓形成等不良事件的人数在两组间无差异,但由于证据质量极低,效应估计值不确定(常规护理组23%(17/75)报告有事件,术前教育组为18%(14/75);风险比(RR)0.79;95%CI 0.19至3.21;2项随机对照试验,150名参与者)。未报告健康相关生活质量、治疗成功的总体评估及再次手术率。在膝关节置换患者中,术前教育可能不会比常规护理带来更多益处。常规护理下术后12个月的平均疼痛评分为100分制中的80分(分数越低表示疼痛越少),术前教育使其降低2分(95%CI -3.45至7.45;1项随机对照试验,109名参与者),绝对风险差为-2%(95%CI -4%至8%)。常规护理下术后12个月的平均功能评分为100分制中的77分(分数越低表示功能越好),术前教育与之无差异(0;95%CI -5.63至5.63;1项随机对照试验,109名参与者),绝对风险差为0%(95%CI -6%至6%)。常规护理下术后12个月的平均健康相关生活质量评分为100分制中的41分(分数越低表示生活质量越差),术前教育使其降低3分(95%CI -6.38至0.38;1项随机对照试验,109名参与者),绝对风险差为-3%(95%CI -6%至1%)。报告感染和深静脉血栓形成等不良事件的人数在两组间无差异(常规护理组18%(11/60)报告有事件,术前教育组为13%(7/55);RR 0.69;95%CI 0.29至1.66;1项随机对照试验,115名参与者),绝对风险差为-6%(-19%至8%)。未报告治疗成功的总体评估、术后焦虑及再次手术率。
尽管术前教育已纳入同意过程,但我们不确定其在减轻焦虑或手术结局(如疼痛、功能和不良事件)方面是否比常规护理更具优势。术前教育可能是一种有用的辅助手段,不良影响风险较低,特别是对于某些患者,例如患有抑郁症、焦虑症或期望不切实际的患者,他们可能对根据其身体、心理和社会需求分层的术前教育反应良好。