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新型改良双极射频消融术对术前合并心房颤动的非体外循环冠状动脉搭桥手术的影响。

Effect of novel modified bipolar radiofrequency ablation for preoperative atrial fibrillation combined with off-pump coronary artery bypass grafting surgery.

作者信息

Jiang Zhaolei, Ma Nan, Tang Min, Liu Hao, Ding Fangbao, Yin Hang, Mei Ju

机构信息

Department of Cardiothoracic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, 1665 Kongjiang Road, Shanghai, 200092, China.

出版信息

Heart Vessels. 2015 Nov;30(6):818-23. doi: 10.1007/s00380-014-0519-2. Epub 2014 May 13.

Abstract

We described a novel modified bipolar radiofrequency (RF) ablation for preoperative atrial fibrillation (AF) combined with off-pump coronary artery bypass grafting (OPCABG) for patients with AF and coronary artery disease (CAD). The aim of this study was to assess the effect of this novel procedure and to determine whether it can eliminate AF for CAD patients. From January 2007 to June 2013, 45 patients (26 male patients) with AF (9 paroxysmal, 17 persistent, and 19 long-standing persistent) and CAD underwent the novel modified bipolar RF ablation combined with OPCABG in our department. After median sternotomy, the modified bipolar RF ablation and OPCABG were performed on beating heart without cardiopulmonary bypass. Pulmonary vein isolation and left atrium ablation were achieved using a bipolar RF champ. Mitral annular lesion and ganglionic plexus were ablated with a bipolar RF pen. The left atrial appendage was excluded using a surgical stapler. 24 h holter monitoring and echocardiography were performed at discharge and 3, 6, 12 months postoperatively as well as every year thereafter. The modified bipolar RF ablation and OPCABG were performed successfully in all patients. Mean AF ablation time was 33.6 ± 4.2 min, and mean OPCABG time was 87.6 ± 13.3 min. Mean postoperative hospital stay was 12.6 ± 5.5 days. The maintenance of sinus rhythm was 95.6 % (43/45) at discharge. There was no early death and permanent pacemaker implantation in perioperation. At a mean follow-up of 29.8 ± 10.2 months, 38 of 45 (84.4 %) patients were in sinus rhythm. Follow-up TTE at 6 months postoperatively showed that left atrial diameter was significantly reduced and left ventricular ejection fraction was significantly increased. The novel modified bipolar RF ablation procedure was safe, feasible and effective. It may be useful in selecting the best ablation approaches for patients with AF and CAD.

摘要

我们描述了一种新型改良双极射频(RF)消融术,用于术前合并心房颤动(AF)的冠状动脉疾病(CAD)患者,该消融术联合非体外循环冠状动脉旁路移植术(OPCABG)进行。本研究的目的是评估这种新手术的效果,并确定其是否能消除CAD患者的AF。2007年1月至2013年6月,45例AF患者(26例男性患者)(9例阵发性、17例持续性和19例长期持续性)合并CAD,在我科接受了新型改良双极RF消融联合OPCABG手术。经正中胸骨切开术后,在心脏跳动且无体外循环的情况下进行改良双极RF消融和OPCABG。使用双极RF champ实现肺静脉隔离和左心房消融。用双极RF笔消融二尖瓣环病变和神经节丛。使用手术吻合器切除左心耳。出院时、术后3个月、6个月、12个月以及此后每年进行24小时动态心电图监测和超声心动图检查。所有患者均成功进行了改良双极RF消融和OPCABG。平均AF消融时间为33.6±4.2分钟,平均OPCABG时间为87.6±13.3分钟。术后平均住院时间为12.6±5.5天。出院时窦性心律维持率为95.6%(43/45)。围手术期无早期死亡和永久性起搏器植入。平均随访29.8±10.2个月时,45例患者中有38例(84.4%)处于窦性心律。术后6个月的随访经胸超声心动图显示左心房直径显著减小,左心室射血分数显著增加。新型改良双极RF消融术安全、可行且有效。它可能有助于为AF合并CAD患者选择最佳消融方法。

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