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加拿大一枝黄花根精油的化学成分及抗菌活性

Chemical composition and antimicrobial activity of solidago canadensis linn. Root essential oil.

作者信息

Mishra Devendra, Joshi Shivani, Bisht Ganga, Pilkhwal Sangeeta

机构信息

Department of Applied Chemistry, Birla Institute of Applied Sciences Bhimtal, Nainital, India.

Department of Chemistry, Kumaun University, Nainital, India.

出版信息

J Basic Clin Pharm. 2010 Jun;1(3):187-90. Epub 2010 Aug 15.

Abstract

The essential oil from the roots of Solidago canadensis Linn. (fam. Asteraceae) was analyzed by GC, GC/MS and NMR spectroscopy. Thirty nine constituents comprising 75.4% of the total oil were identified from the oil. Thymol constituted 20.25% of the oil followed by α-copaene (6.26%) and carvacrol (5.51%). The antimicrobial activity of the oil was evaluated using disc diffusion method. Results showed that the oil exhibited significant antibacterial activity against S. feacalis and E. coli whereas it showed moderate antifungal activity against C. albicans.

摘要

对加拿大一枝黄花(菊科)根部的精油进行了气相色谱(GC)、气相色谱-质谱联用(GC/MS)和核磁共振光谱(NMR)分析。从该精油中鉴定出39种成分,占总油量的75.4%。百里香酚占精油的20.25%,其次是α-可巴烯(6.26%)和香芹酚(5.51%)。采用纸片扩散法评估了该精油的抗菌活性。结果表明,该精油对粪肠球菌和大肠杆菌表现出显著的抗菌活性,而对白色念珠菌表现出中等程度的抗真菌活性。

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