Department of Biomedical Engineering, College of Medical Science, Catholic University of Daegu, Gyeongsan, 712-702, South Korea.
Lasers Med Sci. 2014 Nov;29(6):1829-37. doi: 10.1007/s10103-014-1584-6. Epub 2014 May 15.
Although numerous lasers with different wavelengths are available for laser hair removal, their use in individuals with dark-pigmented skin remains a challenge. The present study aims to develop a numerical heat diffusion model considering skin types over various wavelengths. This numerical mode uses Pennes approximation to represent heat from metabolism, blood perfusion and an external heating source. The heat diffusion model is experimentally validated by using agar-based skin tissue phantoms. Diode lasers with four different wavelengths were used with two antithetical skin models. The pulse width and beam spot size were set to 200 ms and 1 cm(2), respectively. Temperature distribution along the hair structure and skin tissue was examined to determine both thermal confinement and heat transfer to the hair follicle. Experimental results are well matched with the numerical results. The results show that for the light skin model, thermal confinement is well achieved over various wavelengths, and treatment efficacy is expected to be better at a shorter wavelength. Otherwise, for the dark skin model, thermal confinement is poorly achieved as the wavelength decreases (<808 nm) and the temperature gap between the hair tip and the hair root is significantly large compared with the light skin model, which may lead to adverse effects. We believe that the developed numerical model will help to establish optimal laser parameters for different individuals during laser hair removal.
尽管有许多具有不同波长的激光器可用于激光脱毛,但在深色皮肤个体中使用它们仍然是一个挑战。本研究旨在开发一种考虑各种波长的皮肤类型的数值热扩散模型。该数值模型使用 Pennes 近似法来表示来自新陈代谢、血液灌注和外部热源的热量。使用基于琼脂的皮肤组织模型对热扩散模型进行了实验验证。使用了四种不同波长的二极管激光器和两种相反的皮肤模型。脉冲宽度和光束光斑尺寸分别设置为 200ms 和 1cm(2)。检查了沿着毛发结构和皮肤组织的温度分布,以确定热限制和向毛囊的热传递。实验结果与数值结果吻合良好。结果表明,对于浅色皮肤模型,在各种波长下都能很好地实现热限制,并且预计在较短的波长下治疗效果会更好。否则,对于深色皮肤模型,随着波长的降低(<808nm),热限制较差,并且毛发尖端和发根之间的温度差明显大于浅色皮肤模型,这可能导致不良反应。我们相信,所开发的数值模型将有助于在激光脱毛期间为不同个体建立最佳的激光参数。