Wolf I, Bergervoet P W M, Sebens F W, van den Oever H L A, Savelkoul P H M, van der Zwet W C
Laboratory for Medical Microbiology and Infection Control, Deventer Ziekenhuis, The Netherlands.
Laboratory for Medical Microbiology and Infection Control, Deventer Ziekenhuis, The Netherlands.
J Hosp Infect. 2014 Jun;87(2):126-30. doi: 10.1016/j.jhin.2014.02.013. Epub 2014 Apr 18.
Between December 2010 and April 2012, intensive care unit (ICU) patients in our hospital were infrequently colonized with extended-spectrum β-lactamase-positive bacteria (ESBLs). We hypothesized that these ESBLs originated from patients' room sinks, and this was prospectively investigated by weekly culturing of patients and sinks during a 20-week period. ESBLs were isolated from all 13 sinks. Four patients became colonized with ESBLs that were genetically identical to ESBLs that had previously been isolated from the sink. One of these patients died of pneumonia caused by the ESBL. Transmission from sinks to patients was stopped by integrating self-disinfecting siphons to all sinks on the ICU.
2010年12月至2012年4月期间,我院重症监护病房(ICU)的患者很少被产超广谱β-内酰胺酶(ESBLs)的细菌定植。我们推测这些ESBLs源自患者病房的水槽,并在20周内通过每周对患者和水槽进行培养对此进行了前瞻性研究。在所有13个水槽中均分离出了ESBLs。4名患者被与之前从水槽中分离出的ESBLs基因相同的ESBLs定植。其中一名患者死于由该ESBLs引起的肺炎。通过在ICU的所有水槽中安装自消毒虹吸管,阻断了从水槽到患者的传播。