Mukherjee Bipasha, Alam Mohammad Shahid, Krishnakumar S
Orbit and Oculoplasty, Medical Research Foundation , Chennai , India and.
Orbit. 2014 Aug;33(4):314-7. doi: 10.3109/01676830.2014.904381. Epub 2014 May 15.
Castleman disease is a non-neoplastic cause of lymphadenopathy, first described in 1956 by Dr. Benjamin Castleman. Orbital involvement in Castleman disease is extremely rare. We report a case of bilateral orbital Castleman disease in a 48-year-old Asian male who presented with bilateral inferior dystopia. MRI revealed bilateral extraconal superior orbital mass. Histopathology and immunohistochemistry of the mass revealed features of Castleman disease of hyaline vascular type. Castleman disease should be a differential in suspected idiopathic orbital inflammatory disease and lymphoproliferative disorders.
卡斯特尔曼病是淋巴结病的一种非肿瘤性病因，1956年由本杰明·卡斯特尔曼医生首次描述。卡斯特尔曼病累及眼眶极为罕见。我们报告一例48岁亚洲男性双侧眼眶卡斯特尔曼病，患者表现为双侧下睑下垂。磁共振成像显示双侧眶锥外上眶肿块。肿块的组织病理学和免疫组织化学检查显示为透明血管型卡斯特尔曼病的特征。在疑似特发性眼眶炎性疾病和淋巴增殖性疾病时，应将卡斯特尔曼病列为鉴别诊断之一。
