a Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science , Universidade Estadual Paulista (UNESP) , Botucatu , SP , Brazil.
Vet Q. 2014;34(3):167-71. doi: 10.1080/01652176.2014.924166. Epub 2014 Jun 13.
Dioctophyma renale is a large nematode distributed worldwide that may cause progressive and severe destruction of renal parenchyma.
The present study aimed to evaluate pre- and post-operatively dogs submitted to right nephrectomy due to D. renale and to assess the histopathological damage of the removed kidney.
Eight crossbred dogs, aged from 12 to 48 months that were unilaterally nephrectomized due to the presence of D. renale were evaluated. Physical examination, urinalysis, complete blood count, serum biochemistry, and abdominal ultrasound were performed immediately before and one month after nephrectomy. The nephrectomized right kidneys were submitted to macroscopic and microscopic evaluations.
Urinalysis preoperatively detected occult blood in all dogs and D. renale eggs in five cases. Complete blood count showed all parameters within the reference range, except one dog post-operatively. Serum biochemistry performed before and after surgery verified that urea, creatinine and sodium were within the reference range values in all dogs. Other findings varied among the dogs. The length and arterial resistive index mean values of the left kidney were similar pre- and post-operatively.
Thus, the inconsiderable change in laboratory findings pre- and post-operatively was attributable to compensation by left kidney function for the removed abnormal right kidney. Right kidney histology revealed chronic nephropathy due to D. renale.
Imaging diagnosis should be performed on dogs suspected as carrying the disease or on those from an enzootic area since the laboratory findings are not specific except eggs in the urine.
肾膨结线虫是一种广泛分布的大型线虫，可能导致肾实质进行性和严重破坏。
本研究旨在评估因肾膨结线虫而接受右肾切除术的犬的术前和术后情况，并评估切除肾脏的组织病理学损伤。
评估了 8 只 12 至 48 月龄的杂交犬，这些犬因存在肾膨结线虫而单侧接受了肾切除术。在肾切除术前和术后 1 个月进行了体格检查、尿液分析、全血细胞计数、血清生化和腹部超声检查。切除的右肾进行了大体和显微镜评估。
术前尿液分析发现所有犬均存在潜血，5 例存在肾膨结线虫卵。全血细胞计数显示所有参数均在参考范围内，除 1 例术后犬外。术前和术后进行的血清生化检查证实，所有犬的尿素、肌酐和钠均在参考范围值内。其他发现因犬而异。左肾的长度和动脉阻力指数平均值在术前和术后相似。
因此，术前和术后实验室检查结果的变化不大归因于左肾功能对切除的异常右肾的代偿。右肾组织学显示由肾膨结线虫引起的慢性肾病。
应在疑似患有该病的犬或来自地方性流行区的犬中进行影像学诊断，因为除了尿液中的卵之外，实验室检查结果并不特异。
