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医学辐射照射的定量获益-风险分析。

Quantitative benefit-risk analysis of medical radiation exposures.

机构信息

Memorial Sloan Kettering Cancer Center, New York, NY.

Department of Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN.

出版信息

Semin Nucl Med. 2014 May;44(3):210-4. doi: 10.1053/j.semnuclmed.2014.03.010.

DOI:10.1053/j.semnuclmed.2014.03.010
PMID:24832586
Abstract

While it is commonly said that the benefits of the use of radiation in the healing arts far outweigh any potential risks, there has not been to date an attempt to quantify the numerical benefits of uses of medical radiation. Using the 'Linear, No-Threshold' (LNT) model of radiation carcinogenesis, many have provided numerical estimates of the risks of radiation exposure, sometimes in irresponsible ways. In this work, we show, through several selected examples, how the numerical benefits of medical radiation exposures indeed far outweigh any theoretical cancer risks. Choosing more invasive measures, there are known rates of complications that result in mortalities in the patient populations. We note these real risks in the selected examples and compare them to the theoretical risks of cancer predicted by the LNT model.

摘要

虽然人们常说,在医疗艺术中使用辐射的好处远远超过任何潜在的风险,但迄今为止,还没有人试图量化医疗辐射使用的数值收益。许多人使用“线性无阈值”(LNT)模型来对辐射致癌的风险进行数值估计,有时甚至是不负责任的方式。在这项工作中,我们通过几个选定的例子展示了医疗辐射暴露的数值收益确实远远超过任何理论上的癌症风险。选择更具侵入性的措施,就会有已知的并发症发生率导致患者死亡。我们在选定的例子中注意到这些实际风险,并将其与 LNT 模型预测的癌症理论风险进行比较。

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