Ye Anfang, Li Jianing, Hao Xiaoji, Lai Zhongjun, Guo Jiadi, Cao Yiyao, Yu Shunfei, Xuan Zhiqiang
Department of Occupational Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
School of Public Health, Suzhou Medical College of Soochow University, Suzhou, Jiangsu, China.
Front Med (Lausanne). 2025 May 14;12:1600355. doi: 10.3389/fmed.2025.1600355. eCollection 2025.
Lens damage induced by occupational exposure to ionizing radiation has been extensively studied by radiation workers. This study aimed to investigate the factors influencing lens opacity in radiologists exposed to low-dose ionizing radiation.
Medical examination data of 1,456 radiological workers who underwent occupational health checkups between January 2023 and December 2024 were collected, along with their total personal radiation dose over a 10-year period from 2015 to 2024. The relationship between lens opacity and influencing factors such as sex, age, radiation dose, occupational type, and duration of radiation work was analyzed using multivariate logistic regression.
Among the 1,456 radiological workers, 105 cases of lens opacity were detected, with a prevalence rate of 7.21%. The majority of lens opacities were located in the posterior subcapsular region, accounting for 52 cases (49.52%, 52/105). The prevalence of lens opacity revealed a linear increasing trend with age and years of service. In addition, the proportion of lens opacity gradually increased with increasing total and annual radiation doses. Age, occupational type, and total radiation dose were associated with posterior subcapsular opacity. Age and total radiation dose were regarded as independent risk factors [age Odds Ratio (OR), 1.068; 95% confidence interval (CI), 1.035-1.103; total dose OR, 1.111; 95% CI, 1.033-1.194]. The three occupational types with the highest prevalence were nuclear medicine (6/51), radiation therapy (14/240), and interventional radiology (18/340).
The prevalence of lens opacity among radiological workers was associated with age, radiation dose, occupational type, and duration of radiation work. Nuclear medicine poses the highest risk for posterior subcapsular opacity.
职业性接触电离辐射所致晶状体损伤已被放射工作人员广泛研究。本研究旨在调查低剂量电离辐射暴露的放射科医生中影响晶状体混浊的因素。
收集了2023年1月至2024年12月期间接受职业健康检查的1456名放射工作人员的医学检查数据，以及他们在2015年至2024年10年期间的个人总辐射剂量。采用多因素logistic回归分析晶状体混浊与性别、年龄、辐射剂量、职业类型和放射工作年限等影响因素之间的关系。
在1456名放射工作人员中，检测出105例晶状体混浊，患病率为7.21%。大多数晶状体混浊位于后囊下区域，占52例（49.52%，52/105）。晶状体混浊的患病率随年龄和工作年限呈线性增加趋势。此外，晶状体混浊的比例随总辐射剂量和年辐射剂量的增加而逐渐增加。年龄、职业类型和总辐射剂量与后囊下混浊有关。年龄和总辐射剂量被视为独立危险因素[年龄优势比（OR），1.068；95%置信区间（CI），1.035 - 1.103；总剂量OR，1.111；95%CI，1.033 - 1.194]。患病率最高的三种职业类型是核医学（6/51）、放射治疗（14/240）和介入放射学（18/340）。
放射工作人员晶状体混浊的患病率与年龄、辐射剂量、职业类型和放射工作年限有关。核医学导致后囊下混浊的风险最高。
