血小板 αIIbβ3 活化：填补空缺。
Platelet αIIbβ3 activation: filling in the pieces.
机构信息
UNIVERSITY OF PENNSYLVANIA.
出版信息
Blood. 2014 May 15;123(20):3065-7. doi: 10.1182/blood-2014-02-557355.
PMID:24832940
Abstract
In this issue of Blood, Kasirer-Friede and colleagues show that the adhesion and degranulation promoter protein (ADAP) promotes αIIbβ3 activation by presenting the cytoplasmic proteins talin and kindlin to the β3 cytoplasmic tail.
摘要
在本期《Blood》中，Kasirer-Friede 及其同事表明，黏附和解颗粒蛋白（ADAP）通过将细胞质蛋白 talin 和 kindlin 呈现给β3 胞质尾部来促进 αIIbβ3 的激活。
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