基于金纳米簇荧光猝灭的灵敏碘酸盐传感器。

Sensitive iodate sensor based on fluorescence quenching of gold nanocluster.

作者信息

Li Ruiping, Xu Pingping, Fan Jun, Di Junwei, Tu Yifeng, Yan Jilin

机构信息

The Key Lab of Health Chemistry and Molecular Diagnosis of Suzhou, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 199 Ren'ai Road, Industrial Park, Suzhou 215123, China.

出版信息

Anal Chim Acta. 2014 May 27;827:80-5. doi: 10.1016/j.aca.2014.04.013. Epub 2014 Apr 12.

DOI:10.1016/j.aca.2014.04.013

PMID:24832998

Abstract

In this report we described a highly selective and sensitive iodate sensor. Due to its interaction with fluorescent gold nanoclusters, iodate was capable of oxidizing and etching gold core of the nanoclusters, resulting in fluorescence quenching. Furthermore, it was found that extra iodide ion could enhance this etching process, and even a small amount of iodate could lead to significant quenching. Under an optimized condition, linear relationship between the iodate concentration and the fluorescence quenching was obtained in the range 10 nM-1 μM. The developed iodate sensor was found selective and capable of detecting iodate as low as 2.8 nM. The sensor was then applied for the analysis of iodate in real sample and satisfactory recoveries were obtained.

摘要

在本报告中，我们描述了一种高选择性和高灵敏度的碘酸盐传感器。由于其与荧光金纳米团簇的相互作用，碘酸盐能够氧化并蚀刻纳米团簇的金核，导致荧光猝灭。此外，发现额外的碘离子可以增强这种蚀刻过程，即使少量的碘酸盐也会导致显著的猝灭。在优化条件下，碘酸盐浓度与荧光猝灭之间在10 nM - 1 μM范围内呈线性关系。所开发的碘酸盐传感器具有选择性，能够检测低至2.8 nM的碘酸盐。该传感器随后被应用于实际样品中碘酸盐的分析，并获得了令人满意的回收率。