Division of Fetal Medicine and Obstetrics and Gynecology Ultrasound, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY; Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY.
Division of Fetal Medicine and Obstetrics and Gynecology Ultrasound, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY; Department of Obstetrics and Gynecology and Women's Health, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY.
Am J Obstet Gynecol. 2014 Nov;211(5):521.e1-8. doi: 10.1016/j.ajog.2014.05.015. Epub 2014 May 13.
The objective of the study was to compare the 3-dimensional power Doppler (3DPD) of the uteroplacental circulation space in the first trimester between women who subsequently deliver growth-restricted vs normally grown neonates.
This was a prospective observational study of singleton pregnancies at 11-14 weeks' gestation. The 3DPD indices, vascularization index, flow index, and vascularization flow index were determined on a uteroplacental circulation space sphere biopsy with the virtual organ computer-aided analysis program. Growth restriction was defined as a birthweight less than the 10th percentile for gestational age and was evaluated using both population-based and customized birth curves.
Five hundred seventy-seven women were enrolled. Five hundred twenty-six were eligible for analysis using population centiles, and 497 were available for evaluation using customized centiles. There was no difference in the first-trimester 3DPD indices between patients with growth-restricted and normally grown neonates using either curve.
Three-dimensional power Doppler indices of the uteroplacental circulation space in the first trimester are similar between neonates who develop growth restriction and those who will grow normally.
本研究旨在比较生长受限儿与正常儿孕妇早孕期胎盘血流空间的三维能量多普勒(3DPD)。
这是一项 11-14 孕周单胎妊娠的前瞻性观察性研究。采用虚拟器官计算机辅助分析程序对胎盘血流空间球活检进行 3DPD 指数(包括血管化指数、血流指数和血管化血流指数)测定。生长受限定义为出生体重低于胎龄第 10 百分位,并采用基于人群和定制的生长曲线进行评估。
共纳入 577 例孕妇。526 例采用人群百分位数进行分析,497 例采用定制百分位数进行评估。使用两种曲线,生长受限儿与正常儿孕妇的早孕期 3DPD 指数均无差异。
早孕期胎盘血流空间的三维能量多普勒指数在生长受限儿与正常儿之间无差异。