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颞骨放射性骨坏死的CT表现

CT findings in temporal bone osteoradionecrosis.

作者信息

Ahmed Salmaan, Gupta Nakul, Hamilton Jackson D, Garden Adam S, Gidley Paul W, Ginsberg Lawrence E

机构信息

From the *Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center, Houston, TX; †Department of Diagnostic and Interventional Imaging, The University of Texas Medical School at Houston, Houston, TX; ‡Department of Radiation Oncology, and §Department of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, TX.

出版信息

J Comput Assist Tomogr. 2014 Sep-Oct;38(5):662-6. doi: 10.1097/RCT.0000000000000096.

Abstract

PURPOSE

The goal of this study was to describe computed tomographic findings in patients with clinically proven temporal bone (TB) osteoradionecrosis (ORN) (TB-ORN).

MATERIALS AND METHODS

Computed tomographic scans of 20 patients were retrospectively evaluated for bony and soft tissue abnormalities. Clinical severity was graded based on level of therapy administered: mild (observation), moderate (antibiotics/hyperbaric oxygen), or severe (surgery).

RESULTS

Radiation dose to the primary tumor ranged from 30 to 75.6 Gy. Time to onset of ORN from completion of radiation therapy was 2 to 22 years (median, 7 years).

CLINICAL FINDINGS

exposed bone, 20 of the 20 patients; otorrhea, 17 of the 20 patients; hearing loss, 11 of the 20 patients; otalgia, 10 of the 20 patients; facial nerve paralysis, 2 of the 20 patients; gait imbalance, 2 of the 20 patients. Computed tomographic findings: external auditory canal erosions, 18 of the 20 patients; mastoid effusion, 18 of the 20 patients; mastoid bony coalescence, 5 of the 20 patients; enhancing soft tissue, 6 of the 20 patients; soft tissue gas, 6 of the 20 patients; temporomandibular joint/condylar erosion, 3 of the 20 patients.Three patients developed an abscess.

CONCLUSION

Mastoid effusion and external auditory canal erosions are commonly seen with TB-ORN. Clinically moderate or severe cases of TB-ORN are more likely to demonstrate enhancing soft tissue (P = 0.002), soft tissue gas (P = 0.002), and temporomandibular joint involvement (P = 0.07).

摘要

目的

本研究的目的是描述经临床证实的颞骨(TB)放射性骨坏死(ORN)(TB-ORN)患者的计算机断层扫描结果。

材料与方法

回顾性评估20例患者的计算机断层扫描,以观察骨和软组织异常情况。根据所给予的治疗水平对临床严重程度进行分级:轻度(观察)、中度(抗生素/高压氧)或重度(手术)。

结果

原发肿瘤的辐射剂量为30至75.6 Gy。从放疗结束到ORN发病的时间为2至22年(中位数为7年)。

临床发现

20例患者中有20例出现暴露骨;20例患者中有17例出现耳漏;20例患者中有11例出现听力损失;20例患者中有10例出现耳痛;20例患者中有2例出现面神经麻痹;20例患者中有2例出现步态失衡。计算机断层扫描结果:20例患者中有18例出现外耳道侵蚀;20例患者中有18例出现乳突积液;20例患者中有5例出现乳突骨融合;20例患者中有6例出现软组织强化;20例患者中有6例出现软组织积气;20例患者中有3例出现颞下颌关节/髁突侵蚀。3例患者发生脓肿。

结论

乳突积液和外耳道侵蚀在TB-ORN中常见。临床中度或重度TB-ORN病例更可能出现软组织强化(P = 0.002)、软组织积气(P = 0.002)和颞下颌关节受累(P = 0.07)。

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本文引用的文献

2
Incidence of osteoradionecrosis of the temporal bone.颞骨放射性骨坏死的发病率。
ANZ J Surg. 2011 Dec;81(12):876-9. doi: 10.1111/j.1445-2197.2010.05641.x. Epub 2011 Jan 27.
5
The chemoradiation paradigm in head and neck cancer.头颈癌的放化疗模式
Nat Clin Pract Oncol. 2007 Mar;4(3):156-71. doi: 10.1038/ncponc0750.
6
Osteoradionecrosis of the mandible.下颌骨放射性骨坏死
Curr Opin Otolaryngol Head Neck Surg. 2005 Aug;13(4):217-21. doi: 10.1097/01.moo.0000170527.59017.ff.
7
MALIGNANT TUMOURS OF THE EAR.耳部恶性肿瘤
J Laryngol Otol. 1965 Feb;79:85-119. doi: 10.1017/s0022215100063465.
8
Temporal bone necrosis: diagnosis, classification, and management.颞骨坏死:诊断、分类及处理
Otolaryngol Head Neck Surg. 2000 Sep;123(3):252-7. doi: 10.1067/mhn.2000.107459.
10
Systematic management of osteoradionecrosis in the head and neck.头颈部放射性骨坏死的系统管理
Laryngoscope. 1999 Aug;109(8):1324-7; discussion 1327-8. doi: 10.1097/00005537-199908000-00027.

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