Cai Jing, Zhao Ang, Zhao Jinzhuo, Chen Renjie, Wang Weibing, Ha Sandie, Xu Xiaohui, Kan Haidong
School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China.
School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China; Research Institute for the Changing Global Environment and Fudan Tyndall Centre, Fudan University, Shanghai, China; Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP(3)), Fudan University, 130 Dong-An Road, Shanghai 200433, China.
Environ Pollut. 2014 Aug;191:139-44. doi: 10.1016/j.envpol.2014.04.028. Epub 2014 May 14.
Air pollution has been accepted as an important contributor to asthma development and exacerbation. However, the evidence is limited in China. In this study, we investigated the acute effect of air pollution on asthma hospitalization in Shanghai, China. We applied over-dispersed generalized additive model adjusted for weather conditions, day of the week, long-term and seasonal trends. An interquartile range increase in the moving average concentrations of PM10, SO2, NO2 and BC on the concurrent day and previous day corresponded to 1.82%, 6.41%, 8.26% and 6.62% increase of asthmatic hospitalization, respectively. The effects of SO2 and NO2 were robust after adjustment for PM10. The associations appeared to be more evident in the cool season than in the warm season. Our results contribute to the limited data in the scientific literature on acute effects of air pollution on asthma in high exposure settings, which are typical in developing countries.
空气污染已被公认为是导致哮喘发病和加重的一个重要因素。然而，在中国，这方面的证据有限。在本研究中，我们调查了空气污染对中国上海哮喘住院率的急性影响。我们应用了针对天气状况、星期几、长期和季节性趋势进行调整的过度分散广义相加模型。当日和前一日PM10、SO2、NO2和BC移动平均浓度的四分位距增加分别对应哮喘住院率增加1.82%、6.41%、8.26%和6.62%。在对PM10进行调整后，SO2和NO2的影响依然显著。这种关联在凉爽季节似乎比温暖季节更为明显。我们的研究结果为科学文献中关于高暴露环境下空气污染对哮喘急性影响的有限数据做出了贡献，而这种高暴露环境在发展中国家很典型。
Zotero 插件