School of Public Health, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
School of Public Health, Peking University, Beijing, China.
Front Public Health. 2024 Jan 29;12:1346914. doi: 10.3389/fpubh.2024.1346914. eCollection 2024.
This study aimed to explore the relationship between air pollution and hospital admissions for asthma in older adults, and to further assess the health and economic burden of asthma admissions attributable to air pollution.
We collected information on asthma cases in people over 65 years of age from nine cities in Sichuan province, as well as air pollution and meteorological data. The relationship between short-term air pollutant exposure and daily asthma hospitalizations was analyzed using the generalized additive model (GAM), and stratified by gender, age, and season. In addition, we assessed the economic burden of hospitalization for air pollution-related asthma in older adults using the cost of disease approach.
The single pollutant model showed that every 1 mg/m increase in CO was linked with an increase in daily hospitalizations for older adults with asthma, with relative risk values of 1.327 (95% CI: 1.116-1.577) at lag7. Each 10 μg/m increase in NO, O, PM, PM and SO, on asthma hospitalization, with relative risk values of 1.044 (95% CI: 1.011-1.078), 1.018 (95% CI: 1.002-1.034), 1.013 (95% CI: 1.004-1.022), 1.015 (95% CI: 1.003-1.028) and 1.13 (95% CI: 1.041-1.227), respectively. Stratified analysis shows that stronger associations between air pollution and asthma HAs among older adult in females, those aged 65-69 years, and in the warm season, although all of the differences between subgroups did not reach statistical significance. During the study period, the number of asthma hospitalizations attributable to PM, PM, and NO pollution was 764, 581 and 95, respectively, which resulted in a total economic cost of 6.222 million CNY, 4.73 million CNY and 0.776 million CNY, respectively.
This study suggests that short-term exposure to air pollutants is positively associated with an increase in numbers of asthma of people over 65 years of age in Sichuan province, and short-term exposure to excessive PM and NO brings health and economic burden to individuals and society.
本研究旨在探讨空气污染与老年人哮喘住院之间的关系，并进一步评估因空气污染导致的哮喘住院的健康和经济负担。
我们从四川省九个城市收集了 65 岁以上人群哮喘病例的信息，以及空气污染和气象数据。使用广义加性模型（GAM）分析短期空气污染物暴露与每日哮喘住院之间的关系，并按性别、年龄和季节进行分层。此外，我们使用疾病成本法评估了老年人因空气污染相关哮喘住院的经济负担。
单污染物模型显示，CO 每增加 1mg/m³，老年人哮喘住院的日住院率就会增加，相对风险值为 1.327（95%CI：1.116-1.577），在 lag7 时。NO、O、PM、PM 和 SO 每增加 10μg/m³，哮喘住院的相对风险值分别为 1.044（95%CI：1.011-1.078）、1.018（95%CI：1.002-1.034）、1.013（95%CI：1.004-1.022）、1.015（95%CI：1.003-1.028）和 1.13（95%CI：1.041-1.227）。分层分析表明，在女性、65-69 岁年龄组和温暖季节，空气污染与老年哮喘发作之间的关联更强，尽管所有亚组之间的差异均未达到统计学意义。在研究期间，归因于 PM、PM 和 NO 污染的哮喘住院人数分别为 764、581 和 95，导致的总经济成本分别为 622.2 万元、4730 万元和 776 万元。
本研究表明，短期暴露于空气污染物与四川省 65 岁以上人群哮喘住院人数的增加呈正相关，短期暴露于过量的 PM 和 NO 会给个人和社会带来健康和经济负担。
