Benson Erica E, Betsou Fotini, Amaral Raquel, Santos Lília M A, Harding Keith
1 Damar Research Scientists , Cuparmuir, Fife, Scotland, United Kingdom .
Biopreserv Biobank. 2011 Dec;9(4):399-410. doi: 10.1089/bio.2011.0035. Epub 2011 Nov 17.
The Standard PREanalytical Code (SPREC) was developed by the medical/clinical biobanking sector motivated by the need to harmonize biospecimen traceability in preanalytical processes and enable interconnectivity and interoperability between different biobanks, research consortia, and infrastructures. The clinical SPREC (01) consists of standard preanalytical variable options (7-code elements), which comprise published and (ideally) validated methodologies. Although the SPREC has been designed to facilitate clinical research, the concept could have utility in biorepositories and culture collections that service environmental and biodiversity communities. The SPREC paradigm can be applied to different storage regimes across all types of biorepository. The objective of this article is to investigate adapting the code in nonclinical biobanks using algal culture collections and their cryostorage as a case study. The SPREC (01) is recalibrated as a putative code that might be adopted for biobanks holding different types of biodiversity; it is extended to include optional coding from the point of sample collection to postcryostorage manipulations, with the caveat that the processes are undertaken by biorepository personnel.
标准分析前代码（SPREC）由医学/临床生物样本库部门开发，旨在满足在分析前过程中协调生物样本可追溯性的需求，并实现不同生物样本库、研究联盟和基础设施之间的互联互通和互操作性。临床SPREC（01）由标准分析前变量选项（7个代码元素）组成，这些选项包含已发表且（理想情况下）经过验证的方法。尽管SPREC旨在促进临床研究，但该概念可能对服务于环境和生物多样性领域的生物样本库和培养物保藏中心有用。SPREC范式可应用于所有类型生物样本库的不同存储方式。本文的目的是以藻类培养物保藏及其冷冻保存为例，研究在非临床生物样本库中采用该代码。SPREC（01）被重新校准为一种可能被持有不同类型生物多样性的生物样本库采用的假定代码；它被扩展到包括从样本采集到冷冻保存后处理的可选编码，但前提是这些过程由生物样本库人员进行。
