Integrated Biobank of Luxembourg, 6 rue Nicolas Ernest Barblé, L-1210 Luxembourg.
Cancer Epidemiol Biomarkers Prev. 2010 Apr;19(4):1004-11. doi: 10.1158/1055-9965.EPI-09-1268. Epub 2010 Mar 23.
Management and traceability of biospecimen preanalytical variations are necessary to provide effective and efficient interconnectivity and interoperability between Biobanks.
Therefore, the International Society for Biological and Environmental Repositories Biospecimen Science Working Group developed a "Standard PREanalytical Code" (SPREC) that identifies the main preanalytical factors of clinical fluid and solid biospecimens and their simple derivatives.
The SPREC is easy to implement and can be integrated into Biobank quality management systems and databases. It can also be extended to nonhuman biorepository areas. Its flexibility allows integration of new novel technological developments in future versions. SPREC version 01 is presented in this article.
Implementation of the SPREC is expected to facilitate and consolidate international multicenter biomarker identification research and biospecimen research in the clinical Biobank environment.
为了提供生物库之间有效的和高效的互联性和互操作性，有必要管理和跟踪生物样本分析前的变化。
因此，国际生物和环境储存库生物样本科学工作组制定了一个“标准分析前代码”（SPREC），它确定了临床体液和固体生物样本及其简单衍生物的主要分析前因素。
SPREC 易于实施，可以整合到生物库质量管理系统和数据库中。它也可以扩展到非人类生物储存领域。其灵活性允许在未来版本中集成新的新技术发展。本文介绍了 SPREC 版本 01。
预计 SPREC 的实施将促进和巩固国际多中心生物标志物鉴定研究和临床生物库环境中的生物样本研究。
