基于上转换纳米晶的纸片式 DNA 检测，该上转换纳米晶以镧系掺杂的 LiYF4 为基质。
Paper-based DNA detection using lanthanide-doped LiYF4 upconversion nanocrystals as bioprobe.
机构信息
Chemical Sensors Group, Department of Chemical and Physical Sciences, University of Toronto, 3359 Mississauga Road, Mississauga Ontario, Canada, L5L 1C6.
出版信息
Small. 2014 Oct 15;10(19):3912-7. doi: 10.1002/smll.201400683. Epub 2014 May 16.
PMID:24839261
Abstract
A novel sensitive DNA bioassay using lanthanide-doped LiYF4 upconversion nanocrystals as luminescent marker and oligonucleotide hybridization as the selective reaction is developed in a paper-based platform, providing a detection limit of 3.6 fmol.
摘要
一种新型的灵敏 DNA 生物分析方法，使用镧系掺杂 LiYF4 上转换纳米晶体作为发光标记物，寡核苷酸杂交作为选择性反应，在纸基平台上进行，检测限达到 3.6 fmol。
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