Manassis Katharina, Lee Trevor Changgun, Bennett Kathryn, Zhao Xiu Yan, Mendlowitz Sandra, Duda Stephanie, Saini Michael, Wilansky Pamela, Baer Susan, Barrett Paula, Bodden Denise, Cobham Vanessa E, Dadds Mark R, Flannery-Schroeder Ellen, Ginsburg Golda, Heyne David, Hudson Jennifer L, Kendall Philip C, Liber Juliette, Masia-Warner Carrie, Nauta Maaike H, Rapee Ronald M, Silverman Wendy, Siqueland Lynne, Spence Susan H, Utens Elisabeth, Wood Jeffrey J
Department of Psychiatry.
Faculty of Medicine, University of Toronto.
J Consult Clin Psychol. 2014 Dec;82(6):1163-72. doi: 10.1037/a0036969. Epub 2014 May 19.
Meta-analytic studies have not confirmed that involving parents in cognitive behavior therapy (CBT) for anxious children is therapeutically beneficial. There is also great heterogeneity in the type of parental involvement included. We investigated parental involvement focused on contingency management (CM) and transfer of control (TC) as a potential outcome moderator using a meta-analysis with individual patient data.
Investigators of randomized controlled trials (RCTs) of CBT for anxious children, identified systematically, were invited to submit their data. Conditions in each RCT were coded based on type of parental involvement in CBT (i.e., low involvement, active involvement without emphasis on CM or TC, active involvement with emphasis on CM or TC). Treatment outcomes were compared using a 1-stage meta-analysis.
All cases involved in active treatment (894 of 1,618) were included for subgroup analyses. Across all CBT groups, means of clinical severity, anxiety, and internalizing symptoms significantly decreased posttreatment and were comparable across groups. The group without emphasis on CM or TC showed a higher proportion with posttreatment anxiety diagnoses than the low-involvement group. Between posttreatment and 1-year follow-up, the proportion with anxiety diagnoses significantly decreased in CBT with active parental involvement with emphasis on CM or TC, whereas treatment gains were merely maintained in the other 2 groups.
CBT for anxious children is an effective treatment with or without active parental involvement. However, CBT with active parental involvement emphasizing CM or TC may support long-term maintenance of treatment gains. RESULTS should be replicated as additional RCTs are published.
荟萃分析研究尚未证实让父母参与针对焦虑儿童的认知行为疗法(CBT)具有治疗益处。而且所纳入的父母参与类型也存在很大异质性。我们使用个体患者数据进行荟萃分析,调查了以应急管理(CM)和控制权转移(TC)为重点的父母参与作为潜在的结果调节因素。
通过系统识别,邀请了针对焦虑儿童的CBT随机对照试验(RCT)的研究者提交他们的数据。根据父母在CBT中的参与类型(即低参与度、不强调CM或TC的积极参与、强调CM或TC的积极参与)对每个RCT中的情况进行编码。使用单阶段荟萃分析比较治疗结果。
所有参与积极治疗的病例(1618例中的894例)纳入亚组分析。在所有CBT组中,临床严重程度、焦虑和内化症状的均值在治疗后显著降低,且各组之间具有可比性。不强调CM或TC的组治疗后焦虑诊断的比例高于低参与度组。在治疗后至1年随访期间,在父母积极参与且强调CM或TC的CBT中,焦虑诊断的比例显著降低,而在其他两组中治疗效果仅得以维持。
无论父母是否积极参与,针对焦虑儿童的CBT都是一种有效的治疗方法。然而,父母积极参与且强调CM或TC的CBT可能有助于治疗效果的长期维持。随着更多RCT的发表,研究结果应予以重复验证。