Division of Health Sciences Sansom Institute for Health Research University of South Australia Adelaide SA Australia.
Baker IDI Heart and Diabetes Institute Adelaide SA Australia.
J Diabetes Investig. 2014 Feb 12;5(1):94-8. doi: 10.1111/jdi.12120. Epub 2013 Aug 2.
AIMS/INTRODUCTION: To evaluate the effects of a caloric restricted weight loss program with or without supervised resistance exercise training (EX) on diabetes-related emotional distress and quality of life (QOL) in overweight and obese patients with type 2 diabetes.
In a parallel design, 106 men and women with type 2 diabetes were randomized to a prescriptive 16-week caloric restricted diet (D; 6,000-7,000 kJ/day), with (n = 65) or without (n = 41) EX (three times per week). Bodyweight, glycated hemoglobin, diabetes-specific emotional distress (Problem Areas in Diabetes [PAID] questionnaire) and QOL (Diabetes-39 [D-39] questionnaire) was assessed pre- and post-intervention.
A total of 84 participants completed the study (D n = 33, D + EX n = 51). Weight loss was significantly greater in D + EX compared with D (-11.4 ± 5.8 vs -8.8 ± 5.8 kg, P = 0.04 time × diet). Overall, there were significant improvements in glycated hemoglobin, PAID total score and the D-39 dimensions of 'diabetes control', 'anxiety and worry', 'sexual functioning', 'energy and mobility', 'overall rating of QOL' and 'severity of diabetes' (P ≤ 0.01 for time). The D-39 dimension, 'social burden', did not change (P = 0.07 for time). There was no difference between groups in the response for any of these variables (P ≥ 0.10).
A structured caloric restricted diet with or without EX improves emotional distress and QOL in overweight and obese patients with type 2 diabetes. This trial was registered with Australian New Zealand Clinical Trials Registry (http://www.anzctr.org.au; ACTR No: ACTRN12608000206325).
目的/引言:评估热量限制减肥计划对 2 型糖尿病超重和肥胖患者的糖尿病相关情绪困扰和生活质量(QOL)的影响,以及该计划是否联合监督下的抗阻运动训练(EX)。
采用平行设计,106 名 2 型糖尿病患者被随机分为规定热量限制饮食(D;6000-7000 kJ/d)组(n = 65)或饮食联合(n = 41)EX 组(每周 3 次)。在干预前后评估体重、糖化血红蛋白、糖尿病特异性情绪困扰(糖尿病问题区域量表[PAID]问卷)和 QOL(糖尿病-39 量表[D-39])。
共有 84 名参与者完成了研究(D 组 n = 33,D+EX 组 n = 51)。与 D 组相比,D+EX 组体重减轻更明显(-11.4 ± 5.8 与-8.8 ± 5.8 kg,P = 0.04 时间×饮食)。总的来说,糖化血红蛋白、PAID 总分以及 D-39 的“糖尿病控制”、“焦虑和担忧”、“性功能”、“精力和活动能力”、“整体 QOL 评分”和“糖尿病严重程度”维度都有显著改善(P ≤ 0.01 时间)。D-39 的“社会负担”维度没有变化(P = 0.07 时间)。这些变量的任何一个的组间反应都没有差异(P ≥ 0.10)。
有监督的抗阻运动训练联合或不联合结构化热量限制饮食可改善 2 型糖尿病超重和肥胖患者的情绪困扰和 QOL。该试验已在澳大利亚和新西兰临床试验注册中心(http://www.anzctr.org.au;ACTRN 编号:ACTRN12608000206325)注册。