Australian Technology Network Centre for Metabolic Fitness & Nutritional Physiology Research Centre, Sansom Institute for Health Research, University of South Australia, Adelaide, Australia.
Fertil Steril. 2010 Oct;94(5):1812-6. doi: 10.1016/j.fertnstert.2009.11.001. Epub 2009 Dec 11.
To assess the impact of adding exercise to dietary restriction on depressive symptoms and health-related quality of life (HRQOL) in women with polycystic ovary syndrome (PCOS).
Analysis of depression and quality of life outcomes from a randomized, controlled prospective clinical intervention that evaluated the effects on a range of health outcomes in women with PCOS.
Clinical research unit.
PATIENT(S): One hundred four overweight/obese PCOS women (aged 29.3 ± 0.7 years; body mass index [BMI] 36.1 ± 0.5 kg/m(2)).
INTERVENTION(S): Randomized to one of three 20-week lifestyle programs: diet only, diet and aerobic exercise, or diet and combined aerobic-resistance exercise.
MAIN OUTCOME MEASURE(S): Depression and PCOS-specific HRQOL.
RESULT(S): Forty-nine women completed the intervention (diet only = 14, diet and aerobic exercise = 15, diet and combined aerobic-resistance exercise = 20). By week 20 all groups achieved weight loss and had improvements in depression and PCOS-specific HRQOL scores, except for body hair domain score. There was no difference between treatments for all outcomes.
CONCLUSION(S): This study demonstrated that dietary restriction alone and combined with exercise had similar benefits for improving depression and HRQOL scores in overweight and obese women with PCOS.
评估在多囊卵巢综合征（PCOS）女性中，将运动与饮食限制相结合对抑郁症状和健康相关生活质量（HRQOL）的影响。
对一项随机、对照前瞻性临床干预的抑郁和生活质量结果进行分析，该研究评估了对 PCOS 女性一系列健康结果的影响。
临床研究单位。
104 名超重/肥胖的 PCOS 女性（年龄 29.3±0.7 岁；体重指数[BMI]36.1±0.5kg/m²）。
随机分为三种 20 周生活方式方案之一：仅饮食、饮食和有氧运动或饮食和联合有氧-抗阻运动。
抑郁和 PCOS 特异性 HRQOL。
49 名女性完成了干预（仅饮食组=14，饮食和有氧运动组=15，饮食和联合有氧-抗阻运动组=20）。到第 20 周，所有组都实现了体重减轻，并改善了抑郁和 PCOS 特异性 HRQOL 评分，除了体毛域评分。所有结局在治疗之间均无差异。
本研究表明，饮食限制单独和与运动相结合对改善超重和肥胖的 PCOS 女性的抑郁和 HRQOL 评分具有相似的益处。
